Date published: 2026-5-28

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2,4-Dichloroaniline (CAS 554-00-7)

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Alternate Names:
2,4-dichlorobenzenamine
CAS Number:
554-00-7
Molecular Weight:
162.02
Molecular Formula:
C6H5Cl2N
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,4-Dichloroaniline (2,4-DCA), an organic compound classified as an aromatic amine, emerges as a colorless solid with water solubility and a faint odor. The scientific research realm has harnessed the potential of 2,4-Dichloroaniline in multiple investigations, including studies on its biochemical and physiological impacts. Despite its multifaceted applications, the precise mechanism of action for 2,4-Dichloroaniline remains incompletely elucidated. Current knowledge suggests its role as a weak base, facilitating interaction with the acidic cellular environment to form an anionic species. Subsequently, this anionic species engages with other molecules within the cell, yielding a range of effects.


2,4-Dichloroaniline (CAS 554-00-7) References

  1. Metabolic fate of 2,4-dichloroaniline, prochloraz and nonylphenol diethoxylate in rainbow trout: a comparative in vivo/in vitro approach.  |  Cravedi, JP., et al. 2001. Aquat Toxicol. 53: 159-72. PMID: 11408077
  2. Heat shock protein 70 levels in rainbow trout primary epidermal cultures in response to 2,4-dichloroaniline exposure: a novel in vitro aquatic toxicity marker.  |  Kilemade, M. and Mothersill, C. 2001. Environ Toxicol. 16: 253-9. PMID: 11409197
  3. Expression of delayed cell death (DCD) in the progeny of fish cells surviving 2,4-dichloroaniline (2,4-DCA) exposure.  |  Kilemade, M. and Mothersill, C. 2003. Aquat Toxicol. 63: 207-19. PMID: 12711411
  4. [Excretion of p-chloroaniline metabolites into urine. Excretion of 2,4-dichloroaniline and p-chloroformanilide].  |  Yoshida, T., et al. 1992. Sangyo Igaku. 34: 3-9. PMID: 1635272
  5. The spectroscopic (FTIR, FT-IR gas phase and FT-Raman), first order hyperpolarizabilities, NMR analysis of 2,4-dichloroaniline by ab initio HF and density functional methods.  |  Sundaraganesan, N., et al. 2009. Spectrochim Acta A Mol Biomol Spectrosc. 73: 11-9. PMID: 19251476
  6. Acute toxicity of organic chemicals to Gammarus pulex correlates with sensitivity of Daphnia magna across most modes of action.  |  Ashauer, R., et al. 2011. Aquat Toxicol. 103: 38-45. PMID: 21392493
  7. Reductive dehalogenation of dichloroanilines by anaerobic microorganisms in fresh and dichlorophenol-acclimated pond sediment.  |  Struijs, J. and Rogers, JE. 1989. Appl Environ Microbiol. 55: 2527-31. PMID: 2604394
  8. Development of a standardized reproduction toxicity test with the earthworm species Eisenia fetida andrei using copper, pentachlorophenol and 2,4-dichloroaniline.  |  van Gestel, CA., et al. 1989. Ecotoxicol Environ Saf. 18: 305-12. PMID: 2612422
  9. A novel polymer coated magnetic porous carbon nanocomposite derived from a metal-organic framework for multi-target environmental pollutants preconcentration.  |  Asgharinezhad, AA. and Ebrahimzadeh, H. 2020. J Chromatogr A. 1634: 461664. PMID: 33181353
  10. Photocatalytic kinetics of 2,4-dichloroaniline degradation by NiO-clinoptilolite nanoparticles.  |  Iazdani, F. and Nezamzadeh-Ejhieh, A. 2021. Spectrochim Acta A Mol Biomol Spectrosc. 250: 119228. PMID: 33257250
  11. Synthesis, antimicrobial, anti-cancer and in silico studies of new urea derivatives.  |  Sroor, FM., et al. 2021. Bioorg Chem. 112: 104953. PMID: 33964581
  12. Treatment of industrial contaminants with zero-valent iron- and zero-valent aluminium-activated persulfate: a case study with 3,5-dichlorophenol and 2,4-dichloroaniline.  |  Koba Ucun, O., et al. 2021. Turk J Chem. 45: 269-281. PMID: 34104043
  13. Identification, Occurrence, and Cytotoxicity of Haloanilines: A New Class of Aromatic Nitrogenous Disinfection Byproducts in Chloraminated and Chlorinated Drinking Water.  |  Zhang, D., et al. 2022. Environ Sci Technol. 56: 4132-4141. PMID: 35302737
  14. Automated Jendrassik-Grof method for measurement of bilirubin in serum with the Greiner Selective Analyzer (GSA II D), and comparison with the method involving diazotized 2,4-dichloroaniline.  |  Cherian, AG., et al. 1981. Clin Chem. 27: 748-52. PMID: 7226499

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,4-Dichloroaniline, 100 g

sc-238318
100 g
$43.00