Molecular structure of 2,3,4-Tri-O-benzoyl-propofol-β-D-glucuronide Methyl Ester
2,3,4-Tri-O-benzoyl-propofol-β-D-glucuronide Methyl Ester
Application:
2,3,4-Tri-O-benzoyl-propofol-β-D-glucuronide Methyl Ester is a Propofol derivative
Molecular Weight:
680.74
Molecular Formula:
C40H40O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2,3,4-Tri-O-benzoyl-propofol-β-D-glucuronide Methyl Ester is a Propofol (sc-202774) derivative. Propofol is a phenol derivative that is suggested to modulate the sensitivity of capsaicin (sc-3577) to the transient receptor potential vanilloid subtype-1 (TRPV1) receptor. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat.
2,3,4-Tri-O-benzoyl-propofol-β-D-glucuronide Methyl Ester References
- Propofol potentiates ATP-activated currents of recombinant P2X(4) receptor channels expressed in human embryonic kidney 293 cells. | Tomioka, A., et al. 2000. Neurosci Lett. 284: 167-70. PMID: 10773425
- Translocation of protein kinase C isoforms is involved in propofol-induced endothelial nitric oxide synthase activation. | Wang, L., et al. 2010. Br J Anaesth. 104: 606-12. PMID: 20348139
- TRPV1 splice variants: structure and function. | Schumacher, MA. and Eilers, H. 2010. Front Biosci (Landmark Ed). 15: 872-82. PMID: 20515731
- Propofol modulates agonist-induced transient receptor potential vanilloid subtype-1 receptor desensitization via a protein kinase Cepsilon-dependent pathway in mouse dorsal root ganglion sensory neurons. | Wickley, PJ., et al. 2010. Anesthesiology. 113: 833-44. PMID: 20808213
- The effects of propofol and enflurane on single calcium channel currents of guinea-pig isolated ventricular myocytes. | Takahashi, H., et al. 1994. Br J Pharmacol. 111: 1147-53. PMID: 8032601
- Antinociceptive properties of propofol: involvement of spinal cord gamma-aminobutyric acid(A) receptors. | Nadeson, R. and Goodchild, CS. 1997. J Pharmacol Exp Ther. 282: 1181-6. PMID: 9316824
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,3,4-Tri-O-benzoyl-propofol-β-D-glucuronide Methyl Ester, 5 mg | sc-216267 | 5 mg | $300.00 |