Date published: 2026-4-25

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PLEKHG Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PLEKHG monoclonal antibodies for research focused on understanding the PLEKHG protein family. PLEKHG monoclonal antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PLEKHG proteins function as guanine nucleotide exchange factors (GEFs) for Rho GTPases, playing essential roles in regulating cytoskeletal dynamics and cellular signaling pathways. Research has shown significant involvement of PLEKHG proteins in cell migration, adhesion, and proliferation, highlighting their significance in both normal physiology and disease states. PLEKHG proteins have emerged as important factors in cancer development and neurodegenerative conditions. Investigating PLEKHG protein mechanisms can reveal potential therapeutic targets and treatment strategies. Ongoing studies continue to uncover new functions and regulatory mechanisms of PLEKHG proteins in cellular processes. Research utilizing PLEKHG monoclonal antibodies from Santa Cruz Biotechnology contributes to advancing scientific understanding of cellular regulation and disease mechanisms.

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PLEKHG Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PLEKHG5 Antibody (5A9)

sc-517108mouse IgG2a κ896-995 (h)WB, IP, IF, IHC(P), ELISAh

new

(1)

PLEKHG CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PLEKHG4B CRISPR/Cas9 KO Plasmid (h)

sc-407381hGene KnockoutGFP0
(0)

PLEKHG5 CRISPR/Cas9 KO Plasmid (h)

sc-418543hGene KnockoutGFP0
(0)

PLEKHG5 HDR Plasmid (h)

sc-418543-HDRhHomology Directed RepairPuromycin0
(0)

PLEKHG5 Double Nickase Plasmid (h)

sc-418543-NIChGene KnockoutPuromycin0
(0)

PLEKHG5 Double Nickase Plasmid (h2)

sc-418543-NIC-2hGene KnockoutPuromycin0
(0)

PLEKHG siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PLEKHG1 siRNA (h)

sc-95507hGene SilencingN/A0
(0)

PLEKHG1 shRNA Plasmid (h)

sc-95507-SHhGene SilencingPuromycin0
(0)

PLEKHG1 shRNA (h) Lentiviral Particles

sc-95507-VhGene SilencingPuromycin0
(0)

PLEKHG1 siRNA (m)

sc-152311mGene SilencingN/A0
(0)

PLEKHG1 shRNA Plasmid (m)

sc-152311-SHmGene SilencingPuromycin0
(0)

PLEKHG1 shRNA (m) Lentiviral Particles

sc-152311-VmGene SilencingPuromycin0
(0)

PLEKHG2 siRNA (h)

sc-97423hGene SilencingN/A0
(0)

PLEKHG2 shRNA Plasmid (h)

sc-97423-SHhGene SilencingPuromycin0
(0)

PLEKHG2 shRNA (h) Lentiviral Particles

sc-97423-VhGene SilencingPuromycin0
(0)

PLEKHG2 siRNA (m)

sc-152312mGene SilencingN/A0
(0)

PLEKHG2 shRNA Plasmid (m)

sc-152312-SHmGene SilencingPuromycin0
(0)

PLEKHG2 shRNA (m) Lentiviral Particles

sc-152312-VmGene SilencingPuromycin0
(0)

PLEKHG3 siRNA (h)

sc-92185hGene SilencingN/A0
(0)

PLEKHG3 shRNA Plasmid (h)

sc-92185-SHhGene SilencingPuromycin0
(0)

PLEKHG3 shRNA (h) Lentiviral Particles

sc-92185-VhGene SilencingPuromycin0
(0)

PLEKHG3 siRNA (m)

sc-152313mGene SilencingN/A
1
(0)

PLEKHG3 shRNA Plasmid (m)

sc-152313-SHmGene SilencingPuromycin
1
(0)

PLEKHG3 shRNA (m) Lentiviral Particles

sc-152313-VmGene SilencingPuromycin
1
(0)

PLEKHG4B siRNA (h)

sc-91766hGene SilencingN/A0
(0)

PLEKHG4B shRNA Plasmid (h)

sc-91766-SHhGene SilencingPuromycin0
(0)

PLEKHG4B shRNA (h) Lentiviral Particles

sc-91766-VhGene SilencingPuromycin0
(0)

PLEKHG5 siRNA (h)

sc-88767hGene SilencingN/A0
(0)

PLEKHG5 shRNA Plasmid (h)

sc-88767-SHhGene SilencingPuromycin0
(0)

PLEKHG5 shRNA (h) Lentiviral Particles

sc-88767-VhGene SilencingPuromycin0
(0)

PLEKHG5 siRNA (m)

sc-152314mGene SilencingN/A0
(0)

PLEKHG5 shRNA Plasmid (m)

sc-152314-SHmGene SilencingPuromycin0
(0)

PLEKHG5 shRNA (m) Lentiviral Particles

sc-152314-VmGene SilencingPuromycin0
(0)

PLEKHG6 siRNA (h)

sc-95843hGene SilencingN/A0
(0)

PLEKHG6 shRNA Plasmid (h)

sc-95843-SHhGene SilencingPuromycin0
(0)

PLEKHG6 shRNA (h) Lentiviral Particles

sc-95843-VhGene SilencingPuromycin0
(0)

PLEKHG6 siRNA (m)

sc-152315mGene SilencingN/A0
(0)

PLEKHG6 shRNA Plasmid (m)

sc-152315-SHmGene SilencingPuromycin0
(0)

PLEKHG6 shRNA (m) Lentiviral Particles

sc-152315-VmGene SilencingPuromycin0
(0)