Date published: 2026-7-12

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JAK1 Antibodies

Santa Cruz Biotechnology provides a broad selection of JAK1 monoclonal antibodies for investigating Janus kinase 1 (JAK1) in various cellular processes. The monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). JAK1 is a central component of the JAK-STAT signaling pathway, which mediates responses to various cytokines and growth factors. JAK1 plays a fundamental role in immune regulation, hematopoiesis, and cell proliferation. Dysregulation of JAK1 has been linked to several diseases, including autoimmune disorders and cancers, making it an important target for therapeutic intervention. Understanding JAK1's molecular mechanisms and signaling pathways is crucial for developing new therapeutic strategies. Research focusing on JAK1 continues to reveal new insights into cellular communication and disease progression. Investigating JAK1's role in different biological processes can lead to breakthrough discoveries in disease treatment. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance their understanding of JAK1's role in human health and disease.

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JAK1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

JAK1 Antibody (B-3)

sc-376996mouse IgG1 κ270-375 (h)WB, IP, IF, ELISAh
24
(7)

JAK1 Antibody (A-9)

sc-1677mouse IgG2b κ796-815 (m)WB, IP, IF, IHC(P), ELISAm, r, h
26
(12)

JAK1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

JAK1 siRNA (h)

sc-35719hGene SilencingN/A
5
(0)

JAK1 shRNA Plasmid (h)

sc-35719-SHhGene SilencingPuromycin
5
(0)

JAK1 shRNA (h) Lentiviral Particles

sc-35719-VhGene SilencingPuromycin
5
(0)

JAK1 siRNA (m)

sc-35720mGene SilencingN/A
1
(0)

JAK1 shRNA Plasmid (m)

sc-35720-SHmGene SilencingPuromycin
1
(0)

JAK1 shRNA (m) Lentiviral Particles

sc-35720-VmGene SilencingPuromycin
1
(0)

JAK1 CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

JAK1 CRISPR/Cas9 KO Plasmid (h)

sc-400439Gene Knockouth0
(0)

JAK1 HDR Plasmid (h)

sc-400439-HDRHomology Directed Repairh0
(0)

JAK1 CRISPR/Cas9 KO Plasmid (m)

sc-421199Gene Knockoutm0
(0)

JAK1 HDR Plasmid (m)

sc-421199-HDRHomology Directed Repairm0
(0)

JAK1 CRISPR Double Nickase Plasmids

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JAK1 Double Nickase Plasmid (h)

sc-400439-NICGene Knockouth0
(0)

JAK1 Double Nickase Plasmid (h2)

sc-400439-NIC-2Gene Knockouth0
(0)

JAK1 Double Nickase Plasmid (m)

sc-421199-NICGene Knockoutm0
(0)

JAK1 CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

JAK1 CRISPR Activation Plasmid (h)

sc-400439-ACTGene Activationh0
(0)

JAK1 CRISPR Activation Plasmid (m)

sc-421199-ACTGene Activationm0
(0)