Vav Antibody (E-4): sc-17831
- Vav Antibody (E-4) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- raised against amino acids 110-320 mapping to a central domain of Vav of human origin
- Vav Antibody (E-4) is recommended for detection of Vav p95 of human origin by WB, IP, IF and ELISA
- Anti-Vav Antibody (E-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Vav Antibody (E-4) for WB applications. This reagent is now offered in a bundle with Vav Antibody (E-4) (see ordering information below).
QUICK LINKS
Vav Antibody (E-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects Vav p95 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Vav (E-4) antibody is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Vav protein, also known as Vav1 or p95Vav, plays a crucial role in signal transduction pathways, particularly in hematopoietic cells, where Vav is exclusively expressed. Vav protein is characterized by a unique structure, including an N-terminal helix-loop-helix domain and a leucine zipper motif, both essential for mediating interactions with other proteins and facilitating downstream signaling events. An SH2 domain suggests Vav acts as a substrate for tyrosine kinases, linking tyrosine phosphorylation to transcriptional regulation. Oncogenic potential of Vav was first identified through gene transfer assays, highlighting Vav′s importance in cellular signaling and potential implications in cancer biology. Anti-Vav antibody (E-4) enables researchers to explore Vav′s intricate roles in hematopoietic cell signaling and contributions to various physiological and pathological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vav Antibody (E-4) | sc-17831 | 200 µg/ml | $322.00 | |||
Vav Antibody (E-4): m-IgG Fc BP-HRP Bundle | sc-525494 | 200 µg Ab; 10 µg BP | $361.00 | |||
Vav Antibody (E-4) AC | sc-17831 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Vav Antibody (E-4) HRP | sc-17831 HRP | 200 µg/ml | $322.00 | |||
Vav Antibody (E-4) FITC | sc-17831 FITC | 200 µg/ml | $336.00 | |||
Vav Antibody (E-4) PE | sc-17831 PE | 200 µg/ml | $349.00 | |||
Vav Antibody (E-4) Alexa Fluor® 488 | sc-17831 AF488 | 200 µg/ml | $364.00 | |||
Vav Antibody (E-4) Alexa Fluor® 546 | sc-17831 AF546 | 200 µg/ml | $364.00 | |||
Vav Antibody (E-4) Alexa Fluor® 594 | sc-17831 AF594 | 200 µg/ml | $364.00 | |||
Vav Antibody (E-4) Alexa Fluor® 647 | sc-17831 AF647 | 200 µg/ml | $364.00 | |||
Vav Antibody (E-4) Alexa Fluor® 680 | sc-17831 AF680 | 200 µg/ml | $364.00 | |||
Vav Antibody (E-4) Alexa Fluor® 790 | sc-17831 AF790 | 200 µg/ml | $364.00 |