ULK3 Antibody (1404CT148.89.25): sc-517373
- ULK3 Antibody (1404CT148.89.25) is a mouse monoclonal IgG1 κ ULK3 antibody provided at 100 µg/ml
- raised against a synthetic peptide corresponding to amino acids 435-468 in the C-terminal region of ULK3 of human origin
- recommended for detection of ULK3 of mouse, rat and human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ULK3 Antibody (1404CT148.89.25). This work is in progress.
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ULK3 Antibody (1404CT148.89.25) is a mouse monoclonal IgG1 kappa light chain antibody that detects ULK3 protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). Anti-ULK3 antibody (1404CT148.89.25) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important protein. ULK3, or unc-51-like kinase 3, plays a crucial role in cellular processes by regulating autophagy, a vital mechanism for maintaining cellular homeostasis and responding to stress. This 214 amino acid protein contains a protein kinase domain that facilitates the ATP-dependent phosphorylation of target proteins, thereby influencing various signaling pathways. The gene encoding ULK3 is located on human chromosome 15, a region that is rich in genes and accounts for nearly 3% of the human genome. Understanding the function of ULK3 is essential, as its dysregulation has been implicated in several diseases, including cancer and neurodegenerative disorders, making ULK3 a significant target for therapeutic intervention.
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ULK3 Antibody (1404CT148.89.25) References:
- Tissue-specific expression of aryl hydrocarbon receptor and putative developmental regulatory modules in Baltic salmon yolk-sac fry. | Vuori, KA., et al. 2008. Aquat Toxicol. 87: 19-27. PMID: 18294709
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. | Daub, H., et al. 2008. Mol Cell. 31: 438-48. PMID: 18691976
- Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. | Hanks, SK. and Quinn, AM. 1991. Methods Enzymol. 200: 38-62. PMID: 1956325
- The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. | Hanks, SK., et al. 1988. Science. 241: 42-52. PMID: 3291115
- Sequence patterns in protein kinases. | Bairoch, A. and Claverie, JM. 1988. Nature. 331: 22. PMID: 3340146
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ULK3 Antibody (1404CT148.89.25) | sc-517373 | 100 µg/ml | $322.00 |