TNF-R1 Antibody (55R-170): sc-12746
- TNF-R1 Antibody (55R-170) is a Armenian hamster monoclonal IgG, cited in 14 publications, provided at 200 µg/ml
- raised against purified extracellular domain of TNF-R1 of mouse origin
- recommended for detection of TNF-R1 of mouse, rat and human origin by IP and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for neutralization, sc-12746 L, 200 µg/0.1 ml
- See TNF-R1 (H-5): sc-8436 for TNF-R1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TNF-R1 Antibody (55R-170). This work is in progress.
QUICK LINKS
TNF-R1 Antibody (55R-170) is a hamster monoclonal IgG antibody that detects tumor necrosis factor receptor 1 (TNF-R1) in mouse, rat, and human samples through applications such as immunoprecipitation (IP) and flow cytometry (FCM). TNF-R1 plays a crucial role in mediating the effects of tumor necrosis factor, a key cytokine involved in inflammation and immune responses. TNF-R1 is primarily located on the surface of various cell types, including immune cells, where TNF-R1 initiates signaling pathways that can lead to cell survival, proliferation, or apoptosis, depending on the context. TNF-R1′s ability to transduce apoptotic signals is particularly important in regulating immune responses and maintaining tissue homeostasis. Dysregulation of TNF-R1 signaling has been implicated in numerous diseases, including autoimmune disorders and cancer, making TNF-R1 a significant target for therapeutic intervention. TNF-R1 monoclonal antibody (55R-170) is designed to provide reliable detection and characterization of this vital receptor, facilitating research into its role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNF-R1 Antibody (55R-170) | sc-12746 | 200 µg/ml | $322.00 | |||
TNF-R1 Antibody (55R-170) FITC | sc-12746 FITC | 200 µg/ml | $336.00 | |||
TNF-R1 Antibody (55R-170) L | sc-12746 L | 200 µg/0.1 ml | $322.00 | |||
TNF-R1 Antibody (55R-170) PE | sc-12746 PE | 200 µg/ml | $349.00 |