Thy-1/CD90 Antibody (HIS51): sc-19614

Thy-1 Antibody (HIS51) is a mouse monoclonal IgG2a kappa light chain antibody that detects Thy-1 protein in mouse, rat, and human samples by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-Thy-1 antibody (HIS51) is available in non-conjugated form and conjugated to agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® dyes, offering flexibility for various experimental applications. Thy-1, also known as CDw90, is a glycosylphosphatidylinositol-anchored cell surface glycoprotein essential for cell adhesion and signaling, particularly in hematopoietic stem cells. Thy-1 expression helps identify specific cell subpopulations, including those that coexpress CD34, which are considered pluripotent stem cells in bone marrow. Thy-1+ cells play key roles in immunological processes, such as regulating graft versus host disease and autoreactivity after bone marrow transplantation, making Thy-1 an important marker for research and clinical applications.

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Thy-1/CD90 Antibody (HIS51) References:

1. Thy-1 expression in human fibroblast subsets defines myofibroblastic or lipofibroblastic phenotypes.  |  Koumas, L., et al. 2003. Am J Pathol. 163: 1291-300. PMID: 14507638
2. Thy-1 modulates neurological cell-cell and cell-matrix interactions through multiple molecular interactions.  |  Leyton, L. and Hagood, JS. 2014. Adv Neurobiol. 8: 3-20. PMID: 25300130
3. Thy-1 in Integrin Mediated Mechanotransduction.  |  Hu, P. and Barker, TH. 2019. Front Cell Dev Biol. 7: 22. PMID: 30859101
4. Thy-1 as an Integrator of Diverse Extracellular Signals.  |  Hagood, JS. 2019. Front Cell Dev Biol. 7: 26. PMID: 30859102
5. The multiple roles of Thy-1 in cell differentiation and regeneration.  |  Yang, J., et al. 2020. Differentiation. 113: 38-48. PMID: 32403041
6. X-aptamers targeting Thy-1 membrane glycoprotein in pancreatic ductal adenocarcinoma.  |  Wang, H., et al. 2021. Biochimie. 181: 25-33. PMID: 33242496
7. Thy-1 (CD90), Integrins and Syndecan 4 are Key Regulators of Skin Wound Healing.  |  Pérez, LA., et al. 2022. Front Cell Dev Biol. 10: 810474. PMID: 35186924
8. Thy-1 promotes skin fibrosis in SSc.  |  Phillips, R. 2022. Nat Rev Rheumatol. 18: 613. PMID: 36195773
9. Evaluation of salivary Thy-1 in health, periodontitis, and obesity.  |  Al-Ameri, HW., et al. 2024. Oral Dis. 30: 2670-2677. PMID: 37338076
10. Thy-1 restricts steatosis and liver fibrosis in steatotic liver disease.  |  Blank, V., et al. 2024. Liver Int. 44: 2075-2090. PMID: 38702958

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Thy-1/CD90 Antibody (HIS51) has 12 citations in a variety of scientific publications.

Primary antibodies like Anti-Thy-1/CD90 Antibody (HIS51) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Thy-1/CD90 Antibody (HIS51) Specifications

Alternate Product Name: CD90

Product Clone Name: HIS51

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: Thy-1

Epitope Species: rat

Product Reactivity/Detection: Thy-1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 12 citations in various scientific publications

Available Conjugates/Forms for Thy-1/CD90 Antibody (HIS51): AC: Agarose, AF405: Alexa Fluor^® 405, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Thy-1/CD90 antibody is Thy-1/CD90 Antibody (OX7): sc-53116.