Thimet oligopeptidase Antibody (D-10): sc-377153

Thimet oligopeptidase Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects Thimet oligopeptidase in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Thimet oligopeptidase, also known as soluble metallo-endopeptidase, plays a crucial role in the degradation of cytoplasmic peptides, particularly neuropeptides that are less than 20 amino acids in length, which is essential for maintaining cellular homeostasis and regulating various physiological processes. Anti-Thimet oligopeptidase antibody (D-10) targets a protein primarily located in the cytoplasm and highly expressed in the testis, but also found in the liver, lung, and kidney, indicating diverse functional roles across different tissues. The gene encoding Thimet oligopeptidase is mapped to chromosome 19q13.3, and its ability to degrade the β-Amyloid precursor protein and generate amyloidogenic fragments highlights its significance in neurodegenerative diseases. Thimet oligopeptidase monoclonal antibody (D-10) enables researchers to gain valuable insights into the protein′s function and its implications in various biological contexts.

The preferred Thimet oligopeptidase antibody is Thimet oligopeptidase Antibody (4D6): sc-53565.