PPARγ2 Antibody (E-9): sc-390740
- PPARγ2 Antibody (E-9) is a mouse monoclonal IgG1 κ, cited in 11 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-27 of PPARγ2 of mouse origin
- Anti-PPAR gamma 2 Antibody (E-9) is recommended for detection of PPARγ2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-PPAR gamma 2 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PPARγ2 Antibody (E-9) for WB and IHC(P) applications. These reagents are now offered in bundles with PPARγ2 Antibody (E-9) (see ordering information below).
PPARγ2 Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect peroxisome proliferator-activated receptor gamma 2 (PPARγ2) by targeting an epitope within amino acids 2-27 of mouse PPARγ2. Anti-PPARγ2 antibody (E-9) is essential for researchers studying the critical functions of PPARγ2, a key nuclear hormone receptor that plays a vital role in regulating adipocyte differentiation, lipid metabolism, insulin sensitivity, and inflammatory responses. PPARγ2, also known as Nr1c3, PPARgamma, and PPARgamma2, is predominantly localized in the nucleus of cells, where PPARγ2 forms heterodimers with retinoid X receptors (RXRs) to bind specific DNA sequences and modulate the transcription of target genes involved in these metabolic processes. Nuclear localization of PPARγ2 is crucial for function as a transcription factor, enabling direct influence on gene expression in response to various ligands such as prostanoids, fatty acids, and thiazolidinediones. This regulation is fundamental for maintaining energy homeostasis and is implicated in the pathogenesis of several metabolic diseases, including obesity, type 2 diabetes, atherosclerosis, and certain cancers. PPARγ2 monoclonal antibody (E-9) is validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA), ensuring versatility and reliability in diverse experimental settings. Anti-PPARγ2 antibody (E-9) is reactive with PPARγ2 of mouse, rat, and human origin, making PPARγ2 monoclonal antibody (E-9) a versatile tool for cross-species studies. Available in both non-conjugated and various conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® variants, PPARγ2 (E-9) antibody provides researchers with the flexibility to tailor experiments to specific detection and visualization needs. By enabling precise detection and analysis of PPARγ2′s nuclear localization and role in gene regulation, PPARγ2 monoclonal antibody (E-9) supports critical investigations into the molecular mechanisms governing metabolic regulation, the development of therapeutic strategies for related diseases, and the broader understanding of PPARγ2′s impact on cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPARγ2 Antibody (E-9) | sc-390740 | 200 µg/ml | $322.00 | |||
PPARγ2 Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-530246 | 200 µg Ab; 10 µg BP | $361.00 | |||
PPARγ2 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-523660 | 200 µg Ab, 40 µg BP | $361.00 | |||
PPARγ2 Antibody (E-9): m-IgG1 BP-HRP Bundle | sc-543954 | 200 µg Ab; 20 µg BP | $361.00 | |||
PPARγ2 Antibody (E-9) AC | sc-390740 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PPARγ2 Antibody (E-9) HRP | sc-390740 HRP | 200 µg/ml | $322.00 | |||
PPARγ2 Antibody (E-9) FITC | sc-390740 FITC | 200 µg/ml | $336.00 | |||
PPARγ2 Antibody (E-9) PE | sc-390740 PE | 200 µg/ml | $349.00 | |||
PPARγ2 Antibody (E-9) Alexa Fluor® 488 | sc-390740 AF488 | 200 µg/ml | $364.00 | |||
PPARγ2 Antibody (E-9) Alexa Fluor® 546 | sc-390740 AF546 | 200 µg/ml | $364.00 | |||
PPARγ2 Antibody (E-9) Alexa Fluor® 594 | sc-390740 AF594 | 200 µg/ml | $364.00 | |||
PPARγ2 Antibody (E-9) Alexa Fluor® 647 | sc-390740 AF647 | 200 µg/ml | $364.00 | |||
PPARγ2 Antibody (E-9) Alexa Fluor® 680 | sc-390740 AF680 | 200 µg/ml | $364.00 | |||
PPARγ2 Antibody (E-9) Alexa Fluor® 790 | sc-390740 AF790 | 200 µg/ml | $364.00 | |||
PPARγ2 (E-9) Neutralizing Peptide | sc-390740 P | 100 µg/0.5 ml | $69.00 |