Date published: 2026-5-9

1-800-457-3801

SCBT Portrait Logo
Seach Input

Perfluorotetradecanoic acid (CAS 376-06-7)

0.0(0)
Write a reviewAsk a question

CAS Number:
376-06-7
Purity:
≥96%
Molecular Weight:
714.11
Molecular Formula:
C14HF27O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Perfluorotetradecanoic acid (PFTA) is an artificially synthesized fluorinated carboxylic acid with unique characteristics that have found wide application in a variety of sectors. Its hydrophobic nature lends itself well to its utilization as a surfactant, a lubricant, and an additive in the formation of paints and plastics. Perfluorotetradecanoic acid is also integral in the crafting of certain electronic components, including transistors and diodes. Food packaging materials and cosmetic products also benefit from the inclusion of Perfluorotetradecanoic acid in their manufacturing processes. The potential applications of this compound have been a subject of extensive lab research, particularly its role as a surfactant in creating emulsions, which are blends of two or more liquids that typically don′t mix. Further studies have delved into its possible use in creating nanomaterials like nanotubes and nanowires. The exact mechanism of how Perfluorotetradecanoic acid operates remains somewhat elusive, but it is hypothesized that it forms hydrogen bonds with other molecules in a solution, enabling its surfactant properties. It is also believed to form similar bonds with the surface of the substrate it′s applied to, facilitating its function as a lubricant.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences


Perfluorotetradecanoic acid (CAS 376-06-7) References

  1. Gelation of octadecyltrimethoxysilane at the air/water interface: effect of perfluorotetradecanoic acid and divalent cadmium ions.  |  Park, HK., et al. 2004. Langmuir. 20: 4851-8. PMID: 15984241
  2. An ensemble and single-molecule fluorescence microscopy investigation of phase-separated monolayer films stained with Nile Red.  |  Lu, Y., et al. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 78: 216-23. PMID: 21115390
  3. Odd-numbered perfluorocarboxylates predominate over perfluorooctanoic acid in serum samples from Japan, Korea and Vietnam.  |  Harada, KH., et al. 2011. Environ Int. 37: 1183-9. PMID: 21600654
  4. Deposition and photopolymerization of phase-separated perfluorotetradecanoic acid-10,12-pentacosadiynoic acid Langmuir-Blodgett monolayer films.  |  Araghi, HY. and Paige, MF. 2011. Langmuir. 27: 10657-65. PMID: 21761852
  5. Polarized fluorescence microscopy analysis of patterned, polymerized perfluorotetradecanoic acid-pentacosadiynoic acid thin films.  |  Araghi, HY., et al. 2014. Spectrochim Acta A Mol Biomol Spectrosc. 129: 339-44. PMID: 24747858
  6. Mixing Behavior in Binary Anionic Gemini Surfactant-Perfluorinated Fatty Acid Langmuir Monolayers.  |  Rehman, J., et al. 2017. Langmuir. 33: 10205-10215. PMID: 28873306
  7. Perfluoroalkyl substances (PFASs) in the marine environment: Spatial distribution and temporal profile shifts in shellfish from French coasts.  |  Catherine, M., et al. 2019. Chemosphere. 228: 640-648. PMID: 31063911
  8. Immiscible Anionic Gemini Surfactant-Perfluorinated Fatty Acid Langmuir Monolayer Films.  |  Rehman, J., et al. 2019. Langmuir. 35: 10551-10560. PMID: 31309841
  9. Per- and polyfluoroalkyl substances display structure-dependent inhibition towards UDP-glucuronosyltransferases.  |  Liu, YZ., et al. 2019. Environ Pollut. 254: 113093. PMID: 31472452
  10. Single-Molecule Fluorescence Spectroscopy of Phase-Separated 10,12-Pentacosadynoic Acid Films.  |  Yeboah, A., et al. 2021. J Phys Chem B. 125: 3953-3962. PMID: 33826321
  11. Short-term exposure to perfluorotetradecanoic acid affects the late-stage regeneration of Leydig cells in adult male rats.  |  Zhang, S., et al. 2021. Toxicol Appl Pharmacol. 433: 115777. PMID: 34736952
  12. Temporal Trends of Organochlorine and Perfluorinated Contaminants in a Terrestrial Raptor in Northern Europe Over 34 years (1986-2019).  |  Bustnes, JO., et al. 2022. Environ Toxicol Chem. 41: 1508-1519. PMID: 35312196
  13. Leydig cell function in adult male rats is disrupted by perfluorotetradecanoic acid through increasing oxidative stress and apoptosis.  |  Tang, Y., et al. 2022. Environ Toxicol. 37: 1790-1802. PMID: 35385208
  14. Perfluorotetradecanoic Acid (PFTeDA) Induces Mitochondrial Damage and Oxidative Stress in Zebrafish (Danio rerio) Embryos/Larvae.  |  Patel, N., et al. 2022. Toxics. 10: PMID: 36548609
  15. Leydig cell development in pubertal male rats is blocked by perfluorotetradecanoic acid through decreasing AMPK-mTOR-autophagy pathway.  |  Tang, Y., et al. 2023. Toxicol Lett. 383: 43-53. PMID: 37269911

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Perfluorotetradecanoic acid, 5 g

sc-236340
5 g
$83.00

Perfluorotetradecanoic acid, 10 g

sc-236340A
10 g
$189.00

Perfluorotetradecanoic acid, 50 g

sc-236340B
50 g
$903.00

Perfluorotetradecanoic acid, 100 g

sc-236340C
100 g
$1652.00