pan-Cytokeratin Antibody (D-12): sc-17843

pan-Cytokeratin Antibody (D-12) is a mouse monoclonal IgG1 antibody that detects pan-Cytokeratin in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). pan-Cytokeratin is a crucial component of the cytoskeleton in epithelial cells, providing structural support and playing a significant role in maintaining cell shape and integrity. pan-Cytokeratin is primarily located in the cytoplasm, where pan-Cytokeratin forms a network of intermediate filaments that contribute to the mechanical resilience of epithelial tissues. This structural role is particularly important in tissues that experience significant stress, such as the skin and lining of the gastrointestinal tract, as pan-Cytokeratin helps protect against mechanical injury and maintains barrier function. Additionally, specific cytokeratin expression can serve as valuable biomarkers for diagnosing various types of cancers, as different cytokeratin profiles are associated with distinct tumor types, aiding in the characterization and treatment of malignancies. anti-pan-Cytokeratin antibody (D-12) is an essential tool for researchers and clinicians aiming to study epithelial cell biology and cancer pathology.

The preferred pan-Cytokeratin antibody is pan-Cytokeratin Antibody (C11): sc-8018.