PACAP Receptor Antibody (1B5): sc-100315

PACAP Receptor Antibody (1B5) is a mouse monoclonal IgG1 kappa light chain antibody that detects PACAP Receptor protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-PACAP Receptor antibody (1B5) is available as a non-conjugated format. PACAP Receptor, also known as Pituitary adenylate cyclase-activating polypeptide receptor, plays a crucial role in various physiological processes, including neuroprotection, neurogenesis, and stress response modulation. PACAP Receptor is primarily located in the central nervous system and peripheral tissues, where PACAP Receptor regulates neurotransmitter release and neuronal excitability. PACAP Receptor presence in the brain underscores importance in neurodevelopment and neural homeostasis maintenance. As a member of the G-protein coupled receptor family, PACAP Receptor features seven transmembrane domains, which facilitate PACAP ligand binding and activate intracellular signaling pathways like cAMP-protein kinase A. Multiple isoforms produced through alternative splicing allow diverse functional roles in different tissues, making PACAP Receptor a significant target for neurobiology research and potential therapeutic interventions.

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PACAP Receptor Antibody (1B5) References:

1. Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions.  |  Vaudry, D., et al. 2000. Pharmacol Rev. 52: 269-324. PMID: 10835102
2. Overexpression of the human VPAC2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice.  |  Shen, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 11575-80. PMID: 11027354
3. Expression of vasoactive intestinal peptide (VIP) receptors in human uterus.  |  Bajo, AM., et al. 2000. Peptides. 21: 1383-8. PMID: 11072126
4. Vasoactive intestinal peptide: cardiovascular effects.  |  Henning, RJ. and Sawmiller, DR. 2001. Cardiovasc Res. 49: 27-37. PMID: 11121793
5. Selective gene expression and activation-dependent regulation of vasoactive intestinal peptide receptor type 1 and type 2 in human T cells.  |  Lara-Marquez, M., et al. 2001. J Immunol. 166: 2522-30. PMID: 11160313
6. Regulation of vasoactive intestinal peptide receptor expression in developing nervous systems.  |  Karacay, B., et al. 2000. Ann N Y Acad Sci. 921: 165-74. PMID: 11193820
7. Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors in the brain.  |  Shioda, S. 2000. Kaibogaku Zasshi. 75: 487-507. PMID: 11197592

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-PACAP Receptor Antibody (1B5) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-PACAP Receptor Antibody (1B5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

PACAP Receptor Antibody (1B5) Specifications

Alternate Product Name: ADCYAP1R1

Product Clone Name: 1B5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 21-121

Epitope Target: PACAP Receptor

Epitope Species: human

Product Reactivity/Detection: PACAP Receptor

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for PACAP Receptor Antibody (1B5): N/A