NAB2 Antibody (D-7): sc-48416
- NAB2 Antibody (D-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 346-525 of NAB2 of human origin
- recommended for detection of NAB2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See NAB2 (1C4): sc-23867 for NAB2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NAB2 Antibody (D-7) for WB applications. These reagents are now offered in bundles with NAB2 Antibody (D-7) (see ordering information below).
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NAB2 Antibody (D-7) is a mouse monoclonal IgG2a antibody that detects NAB2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NAB2 plays a crucial role in transcriptional regulation as a corepressor of Egr-1/NGFI-A, interacting with DNA-bound transcription factors to modulate gene expression. NAB2 is primarily localized in the nucleus, where NAB2 is essential for the downregulation of NGFI-A activity, thereby influencing vital cellular processes such as cell division, differentiation, and apoptosis. NAB2′s nuclear localization is critical for maintaining cellular homeostasis and preventing uncontrolled cell proliferation, which is particularly relevant in cancer biology. NAB2 is located at chromosome 12q13.3-14.1, a genomic region frequently rearranged in various solid tumors, lipomas, and liposarcomas, highlighting NAB2′s potential as a biomarker for cancer research. Anti-NAB2 antibody (D-7) is an invaluable tool for researchers investigating the intricate mechanisms of transcriptional regulation and its implications in disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NAB2 Antibody (D-7) | sc-48416 | 200 µg/ml | $322.00 | |||
NAB2 Antibody (D-7): m-IgG Fc BP-HRP Bundle | sc-536837 | 200 µg Ab; 10 µg BP | $361.00 | |||
NAB2 Antibody (D-7): m-IgGκ BP-HRP Bundle | sc-534004 | 200 µg Ab; 40 µg BP | $361.00 | |||
NAB2 Antibody (D-7): m-IgG2a BP-HRP Bundle | sc-547881 | 200 µg Ab; 10 µg BP | $361.00 |