IRF-5 Antibody (C-6): sc-390364

IRF-5 Antibody (C-6) is a mouse monoclonal IgG2b kappa light chain antibody that detects IRF-5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). IRF-5 (C-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Interferon regulatory factor 5 (IRF-5) is a crucial member of the IRF family of DNA-binding proteins, which also includes IRF-1, IRF-2, IRF-3, IRF-4, IRF-6, IRF-7, ISGF-3γ p48, and interferon consensus sequence-binding protein (ICSBP). This family plays a vital role in regulating interferon and interferon-inducible genes, with IRF-5 specifically acting as a direct transducer of virus-mediated signaling. IRF-5 is primarily located in the nucleus, where IRF-5 binds to DNA and regulates transcription of various cytokines and chemokines, making IRF-5 essential for immune response to viral infections. Additionally, IRF-5 interacts with several other proteins, including p53, which influences IRF-5′s role in cell cycle regulation and apoptosis, although IRF-5′s pro-apoptotic effects are independent of p53. IRF-5′s ability to modulate immune responses highlights IRF-5′s importance in both innate and adaptive immunity, making anti-IRF-5 antibody (C-6) a valuable tool for researchers studying immune signaling pathways and their implications in disease.

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LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-IRF-5 Antibody (C-6) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-IRF-5 Antibody (C-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

IRF-5 Antibody (C-6) Specifications

Alternate Product Name: IRF-5

Product Clone Name: C-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 443-498

Epitope Target: IRF-5

Epitope Species: human

Product Reactivity/Detection: IRF-5

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for IRF-5 Antibody (C-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred IRF-5 antibody is IRF-5 Antibody (10T1): sc-56714.