IL-13 Antibody (A130D 12G5 1E4): sc-101407
- IL-13 Antibody (A130D 12G5 1E4) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant IL-13 of rat origin
- recommended for detection of recombinant and native IL-13 of mouse and rat origin by WB, FCM and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-13 Antibody (A130D 12G5 1E4). This work is in progress.
QUICK LINKS
SEE ALSO...
IL-13 Antibody (A130D 12G5 1E4) is a mouse monoclonal IgG1 antibody that detects interleukin-13 (IL-13) in mouse and rat samples through applications such as western blotting (WB), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Anti-IL-13 antibody (A130D 12G5 1E4) plays a crucial role in the study of immune responses, as IL-13 is a pleiotropic cytokine that significantly influences the behavior of various immune cells, including monocytes, macrophages, and B cells. IL-13 (A130D 12G5 1E4) monoclonal antibody enables research into this cytokine′s ability to upregulate CD23 expression and major histocompatibility complex (MHC) proteins while downregulating CD14, thereby modulating inflammatory responses. IL-13′s structure is particularly important, containing five cysteine residues that are essential for maintaining stability and biological activity through disulfide bond formation. Additionally, IL-13 features multiple N-linked glycosylation sites, which are critical for proper folding, secretion, and interaction with receptors. Understanding these structural characteristics is vital for elucidating the mechanisms by which IL-13 exerts effects on immune regulation and inflammation, making IL-13 (A130D 12G5 1E4) antibody an invaluable tool for researchers investigating cytokine signaling pathways and their implications in various diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
IL-13 Antibody (A130D 12G5 1E4) References:
- Molecular cloning of the rat IL-13 alpha 2 receptor cDNA and its expression in rat tissues. | Wu, AH. and Low, WC. 2002. J Neurooncol. 59: 99-105. PMID: 12241113
- IL-13 and IL-1beta promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Ralpha. | Ingram, JL., et al. 2004. FASEB J. 18: 1132-4. PMID: 15155567
- IL-33 mediates the expressions of IL-5 and IL-13 in Angiostrongylus cantonensis-infected mice. | Du, WY., et al. 2013. Exp Parasitol. 135: 587-94. PMID: 24076431
- Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13. | Gao, S., et al. 2015. J Mol Cell Cardiol. 85: 131-9. PMID: 25944087
- IL-13 promotes in vivo neonatal cardiomyocyte cell cycle activity and heart regeneration. | Wodsedalek, DJ., et al. 2019. Am J Physiol Heart Circ Physiol. 316: H24-H34. PMID: 30339498
- IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury. | Miao, W., et al. 2020. J Immunol. 204: 1486-1498. PMID: 32034062
- Construction of IL-13 Receptor α2-Targeting Resveratrol Nanoparticles against Glioblastoma Cells: Therapeutic Efficacy and Molecular Effects. | Lin, XM., et al. 2021. Int J Mol Sci. 22: PMID: 34638961
- Regulation of the NF-κB signaling pathway and IL-13 in asthmatic rats by aerosol inhalation of the combined active constituents of Punica granatum juice and peel. | Shaban, NZ., et al. 2022. Biomed Pharmacother. 155: 113721. PMID: 36152413
- Cloning of rat interleukin-13 (IL-13) cDNA and analysis of IL-13 gene expression in experimental glomerulonephritis. | Lakkis, FG. and Cruet, EN. 1993. Biochem Biophys Res Commun. 197: 612-8. PMID: 7916615
- Structural comparison and chromosomal localization of the human and mouse IL-13 genes. | McKenzie, AN., et al. 1993. J Immunol. 150: 5436-44. PMID: 8099936
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-13 Antibody (A130D 12G5 1E4) | sc-101407 | 100 µg/ml | $322.00 |