HPRT Antibody (F-4): sc-376922
- HPRT Antibody (F-4) is a mouse monoclonal IgM κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 167-201 near the C-terminus of HPRT of human origin
- recommended for detection of HPRT of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HPRT Antibody (F-4). This work is in progress.
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SEE ALSO...
HPRT Antibody (F-4) is a mouse monoclonal IgM antibody that detects hypoxanthine phosphoribosyltransferase 1 (HPRT) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). HPRT is a crucial enzyme in purine metabolism, functioning as a purine salvage enzyme that catalyzes the conversion of hypoxanthine and guanine into their respective mononucleotides, inosine monophosphate and guanosine monophosphate. This enzymatic activity maintains nucleotide pools within cells, essential for DNA and RNA synthesis, playing a significant role in cellular proliferation and overall metabolic health. HPRT exists as a homotetramer and requires magnesium ions as cofactors for activity, highlighting the importance of metal ion homeostasis in cellular functions. Deficiencies in HPRT can lead to severe metabolic disorders such as gout and Lesch-Nyhan syndrome, underscoring HPRT′s critical role in purine metabolism and the potential consequences of dysfunction. Anti-HPRT antibody (F-4) provides a reliable tool for researchers studying these pathways and their implications in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HPRT Antibody (F-4) | sc-376922 | 200 µg/ml | $322.00 | |||
HPRT (F-4) Neutralizing Peptide | sc-376922 P | 100 µg/0.5 ml | $69.00 |