Helicobacter pylori OMP Antibody (6621): sc-58137

Helicobacter pylori OMP Antibody (6621) is a mouse monoclonal IgG1 antibody that detects Helicobacter pylori with species reactivity specific to Helicobacter pylori by western blotting (WB) and immunofluorescence (IF). Helicobacter pylori is a spiral-shaped Gram-negative bacterium that uniquely thrives in the highly acidic environment of the stomach, where Helicobacter pylori can cause significant gastrointestinal issues, including peptic ulcers and gastritis. Helicobacter pylori outer membrane proteins (OMPs) play a crucial role in Helicobacter pylori′s ability to adhere to the gastric epithelium, facilitating colonization and persistence within the host. OMPs interact with membrane-associated lipids and carbohydrates, which not only aids in adhesion but also triggers signal transduction events in host cells, potentially leading to inflammatory responses. Understanding the function of OMPs is vital, as OMPs are key factors in the pathogenesis of Helicobacter pylori infections and can influence the severity of associated diseases. Helicobacter pylori OMP (6621) monoclonal antibody is an essential tool for researchers studying the mechanisms of infection and bacterial interactions with host tissues, providing insights that could lead to improved therapeutic strategies.

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Helicobacter pylori OMP Antibody (6621) References:

1. OMP gene deletion results in an alteration in odorant-induced mucosal activity patterns.  |  Youngentob, SL., et al. 2003. J Neurophysiol. 90: 3864-73. PMID: 12917392
2. Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28.  |  Le, PN., et al. 2015. Pharmacol Ther. 146: 1-11. PMID: 25172549
3. The one-minute preceptor model: A systematic review.  |  Gatewood, E. and De Gagne, JC. 2019. J Am Assoc Nurse Pract. 31: 46-57. PMID: 30431548
4. Phenotype annotation with the ontology of microbial phenotypes (OMP).  |  Siegele, DA., et al. 2019. J Biomed Semantics. 10: 13. PMID: 31307550
5. How BamA recruits OMP substrates via poly-POTRAs domain.  |  Ma, X., et al. 2019. FASEB J. 33: 14690-14702. PMID: 31702961
6. The γ-OMP Algorithm for Feature Selection With Application to Gene Expression Data.  |  Tsagris, M., et al. 2022. IEEE/ACM Trans Comput Biol Bioinform. 19: 1214-1224. PMID: 33035156
7. Interaction of 43K OMP of Fusobacterium necrophorum with fibronectin mediates adhesion to bovine epithelial cells.  |  He, X., et al. 2022. Vet Microbiol. 266: 109335. PMID: 35121302
8. Anti-NOTCH1 therapy with OMP-52 M51 inhibits salivary adenoid cystic carcinoma by depressing epithelial-mesenchymal transition (EMT) process and inducing ferroptosis.  |  Li, R., et al. 2024. Toxicol Appl Pharmacol. 484: 116825. PMID: 38253083
9. I-OMP: an improved OMP algorithm for channel state identification in an underwater wireless optical communication scenario.  |  Gao, S., et al. 2024. Appl Opt. 63: 1546-1552. PMID: 38437367
10. An Improved OMP Algorithm for Enhancing the Anti-Interference Performance of Array Antennas.  |  Gao, M., et al. 2024. Sensors (Basel). 24: PMID: 38610502

The preferred Helicobacter pylori OMP antibody is Helicobacter pylori OMP Antibody (BDI176): sc-57779.