Dhh Antibody (A-12): sc-133244

Dhh Antibody (A-12) is a mouse monoclonal IgG2a antibody that detects Dhh in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dhh, or Desert hedgehog, plays a crucial role in embryonic development and tissue patterning by mediating cell-cell interactions, particularly in the development of the nervous system and limbs. Dhh is secreted and functions as a signaling molecule, influencing the behavior of neighboring cells during critical stages of development. Desert hedgehog (Dhh) regulates various cellular processes, including proliferation, differentiation, and survival, which are essential for proper organ formation and function. Additionally, Desert hedgehog interacts with specific receptors, such as Patched and Smoothened, which are integral to the Hedgehog signaling pathway, further underscoring its significance in developmental biology and potential implications in cancer research. Anti-Dhh antibody (A-12) is an invaluable tool for researchers studying these complex biological processes and the underlying mechanisms of diseases associated with Hedgehog signaling dysregulation.

The preferred Dhh antibody is Dhh Antibody (F-9): sc-271168.