
DDX11 Antibody (F-10) is a mouse monoclonal IgG1 antibody that detects DDX11 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DDX11, also known as CHLR1 or KRG2, is a crucial member of the DEAD-box protein family, characterized by the conserved Asp-Glu-Ala-Asp motif, and is known for essential roles in RNA metabolism and chromosomal dynamics. DDX11 is primarily localized in the nucleus, where DDX11 plays a vital role in maintaining genomic stability by facilitating proper chromosome segregation during cell division. DDX11′s ATPase and DNA helicase activities are critical for unwinding DNA and RNA structures, which is particularly important during processes such as embryonic development and cellular growth. DDX11 interacts with various proteins involved in the assembly of ribonucleoprotein complexes, further underscoring DDX11′s significance in cellular function. Five isoforms of DDX11, resulting from alternative splicing, add another layer of complexity to DDX11′s regulatory mechanisms and functional diversity, making anti-DDX11 antibody (F-10) an invaluable tool for researchers studying these intricate biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DDX11 Antibody (F-10) | sc-515168 | 200 µg/ml | $322.00 | |||
DDX11 Antibody (F-10): m-IgG Fc BP-HRP Bundle | sc-538754 | 200 µg Ab; 10 µg BP | $361.00 | |||
DDX11 Antibody (F-10): m-IgGκ BP-HRP Bundle | sc-536422 | 200 µg Ab; 40 µg BP | $361.00 | |||
DDX11 Antibody (F-10): m-IgG1 BP-HRP Bundle | sc-545867 | 200 µg Ab; 20 µg BP | $361.00 | |||
DDX11 (F-10) Neutralizing Peptide | sc-515168 P | 100 µg/0.5 ml | $69.00 |