cleaved NFKBIA/IkB alpha Antibody (5D1623): sc-52900
- cleaved NFKBIA/IkB alpha Antibody (5D1623) is a mouse monoclonal IgG1 cleaved NFKBIA/IkB alpha antibody, cited in 7 publications, provided at 100 µg/ml
- raised against synthetic IκB-α of human origin
- recommended for detection of cleaved IκB-α of human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for cleaved NFKBIA/IkB alpha Antibody (5D1623). This work is in progress.
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Cleaved IκB-α Antibody (5D1623) is a mouse monoclonal IgG1 kappa light chain antibody that detects the cleaved I kappa B-alpha protein of human origin by western blotting (WB). Anti-cleaved I kappa B-alpha antibody (5D1623) is available as a non-conjugated format, providing researchers with a reliable tool for studying the NFκB signaling pathway. Cleaved I kappa B-alpha protein plays a crucial role in regulating NFκB, a transcription factor pivotal in controlling immune responses, inflammation, and cell survival. Upon stimulation by various signals, I kappa B-alpha is phosphorylated and subsequently degraded, allowing NFκB to translocate to the nucleus and activate target genes. This process is essential for proper immune system functioning, as dysregulation can lead to chronic inflammatory diseases and cancer. Understanding I kappa B-alpha cleavage dynamics and implications in cellular signaling pathways is vital for developing therapeutic strategies targeting NFκB-related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cleaved NFKBIA/IkB alpha Antibody (5D1623) | sc-52900 | 100 µg/ml | $322.00 |