CD10 Antibody (CB-Calla): sc-52455
- CD10 Antibody (CB-Calla) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- recommended for detection of CD10 of human origin by IF and FCM
- available conjugated to either phycoerythrin, FITC, Alexa Fluor® 488 or Alexa Fluor® 647 for IF, IHC(P) and FCM
- See CD10 (F-4): sc-46656 for CD10 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD10 Antibody (CB-Calla). These reagents are now offered in bundles with CD10 Antibody (CB-Calla) (see ordering information below).
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CD10 Antibody (CB-Calla) is a mouse monoclonal IgG2b light chain antibody that detects CD10 in human samples through immunofluorescence (IF) and flow cytometry (FCM) applications. CD10, also known as the common acute lymphoblastic leukemia antigen (CALLA) and neutral endopeptidase (NEP), is a type II integral membrane glycoprotein that plays a crucial role in regulating various biological processes by acting as a zinc metalloprotease. Anti-CD10 antibody (CB-Calla) recognizes an enzyme that cleaves a range of biologically active peptides, including Angiotensins I and II, which are vital for blood pressure regulation and fluid balance in the body. CD10 expression is prominent in early B and T lymphoid precursors, B blasts, certain granulocytes, bone marrow stromal cells, and specific epithelial cells, including some tumor cell lines. CD10 presence serves as an important marker for diagnosing common acute lymphocytic leukemias and certain lymphomas, making CD10 (CB-Calla) antibody an essential tool for researchers and clinicians aiming to understand and diagnose hematological malignancies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD10 Antibody (CB-Calla) References:
- CD10 and CD19 fluorescence intensity of B-cell precursors in normal and leukemic bone marrow. Clinical characterization of CD10(+strong) and CD10(+weak) common acute lymphoblastic leukemia. | Rego, EM., et al. 1999. Leuk Res. 23: 441-50. PMID: 10374858
- Clinicopathologic analysis of CD10+ and CD10- diffuse large B-cell lymphoma. Identification of a high-risk subset with coexpression of CD10 and bcl-2. | Xu, Y., et al. 2001. Am J Clin Pathol. 116: 183-90. PMID: 11488064
- HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells. | Dall'Era, MA., et al. 2007. Prostate. 67: 714-21. PMID: 17342744
- CD10 is frequently expressed in classical seminomas. | Del Sordo, R., et al. 2014. Histol Histopathol. 29: 101-6. PMID: 23857215
- The common acute lymphoblastic leukemia antigen (CD10)--emancipation from a functional enigma. | LeBien, TW. and McCormack, RT. 1989. Blood. 73: 625-35. PMID: 2465037
- Role of CD10 Immunohistochemical Expression in Predicting Aggressive Behavior of Phylloides Tumors. | Tariq, MU., et al. 2015. Asian Pac J Cancer Prev. 16: 3147-52. PMID: 25921112
- High expression of CD10 in anaplastic thyroid carcinomas. | Nakazawa, T., et al. 2018. Histopathology. 73: 492-499. PMID: 29791034
- Expression of CD10 in urothelial carcinoma of the bladder and its correlation with histopathological grade, pathological stage, and survival of patients. | Shukla, SK., et al. 2021. J Cancer Res Ther. 17: 887-892. PMID: 34528537
- Cooccurrence of CD10-Positive and CD10-Negative Mantle Cell Lymphoma Complicated With Central Nervous System Involvement Solely by CD10-Positive Population. | Fukushima, N., et al. 2022. Cureus. 14: e21341. PMID: 35186599
- Muramyl dipeptide CD10 monoclonal antibody immunoconjugates inhibited acute leukemia in nude mice. | Wang, Y., et al. 2023. Biosci Rep. 43: PMID: 37039042
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD10 Antibody (CB-Calla) | sc-52455 | 200 µg/ml | $322.00 | |||
CD10 Antibody (CB-Calla): m-IgG Fc BP-HRP Bundle | sc-536856 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD10 Antibody (CB-Calla): m-IgGκ BP-HRP Bundle | sc-534023 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD10 Antibody (CB-Calla): m-IgG2b BP-HRP Bundle | sc-549837 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD10 Antibody (CB-Calla) Alexa Fluor® 488 | sc-52455 AF488 | 200 µg/ml | $364.00 | |||
CD10 Antibody (CB-Calla) Alexa Fluor® 647 | sc-52455 AF647 | 200 µg/ml | $364.00 | |||
CD10 Antibody (CB-Calla) FITC | sc-52455 FITC | 200 µg/ml | $336.00 | |||
CD10 Antibody (CB-Calla) PE | sc-52455 PE | 200 µg/ml | $349.00 |