BRF2 Antibody (F-3): sc-271587
- BRF2 Antibody (F-3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 371-405 at the C-terminus of BRF2 of human origin
- recommended for detection of BRF2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for BRF2 Antibody (F-3) for WB applications. These reagents are now offered in bundles with BRF2 Antibody (F-3) (see ordering information below).
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BRF2 Antibody (F-3) is a mouse monoclonal IgG1 antibody that detects BRF2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BRF2 plays a crucial role in the transcriptional regulation of RNA polymerase III, specifically at type 3 promoters like the human U6 small nuclear RNA promoter. Unlike BRF1, which forms a stable complex with TATA-binding protein (TBP), BRF2 is characterized by association with the TFIIB-related factor, leading to a more dynamic interaction that is essential for the precise regulation of gene expression. This unique structural feature of BRF2 allows for the recruitment of RNA polymerase III to the promoter, facilitating the transcription of small non-coding RNAs that are vital for various cellular processes, including RNA processing and ribosome biogenesis. BRF2 (F-3) antibody serves as an invaluable tool for researchers studying the intricate mechanisms of transcription regulation and the functional implications of RNA polymerase III activity in human cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BRF2 Antibody (F-3) | sc-271587 | 200 µg/ml | $322.00 | |||
BRF2 Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-540250 | 200 µg Ab; 10 µg BP | $361.00 | |||
BRF2 Antibody (F-3): m-IgG1 BP-HRP Bundle | sc-541999 | 200 µg Ab; 20 µg BP | $361.00 | |||
BRF2 (F-3) Neutralizing Peptide | sc-271587 P | 100 µg/0.5 ml | $69.00 |