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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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β-defensin 2 Antibody (2-RY8) is a high quality monoclonal beta-defensin 2 antibody (also designated beta-Defensin 2 antibody or BD-2 antibody) suitable for the detection of the beta-defensin 2 protein of human origin. β-defensin 2 Antibody (2-RY8) is available as the non-conjugated anti-beta-defensin 2 antibody. β-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with β-defensin 2 (2-RY8): sc-134314 antibody?
Gefragt von: AbPolly
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Rated 1 von
IHC Assay Review for Beta-Defensin-2 mABApplication: Immunohistochemistry.
Protocol: Standard protocol for saliva smear staining.
Dilutions tested: 1:10, 1:30, 1:90, 1:270.
Results: Specific stain not detected even at dilution factor of 10.
Rated 5 von
western blot detectionIt worked with succes for western blot detect β-defensin 2,WB 1:1000,The samples were 293T cells,the band at 5kda.Recommend use 15% SDS-PAGE,since the MW is low.
Rated 5 von
Western blotWestern blot detection of good human cells, WB diluted 1:1000 clear band.
Rated 3 von
Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
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