adenosine deaminase Antibody (D-10): sc-376889
- adenosine deaminase Antibody (D-10) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 335-363 at the C-terminus of adenosine deaminase of human origin
- recommended for detection of adenosine deaminase of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for adenosine deaminase Antibody (D-10) for WB and IHC(P) applications. These reagents are now offered in bundles with adenosine deaminase Antibody (D-10) (see ordering information below).
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Adenosine deaminase Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects adenosine deaminase in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Adenosine deaminase plays a crucial role in regulating extracellular adenosine levels, which is vital for maintaining lymphocyte function and preventing toxicity; excessive adenosine can lead to lymphocyte apoptosis and impaired immune responses. Adenosine deaminase primarily exists as a monomer but can associate with adenosine deaminase-binding protein in certain tissues, highlighting its dynamic nature and potential regulatory mechanisms. Deficiencies in adenosine deaminase can result in severe combined immunodeficiency disease (SCID), underscoring its essential function in the immune system. Elevated levels of adenosine deaminase have been linked to hereditary hemolytic anemia, indicating involvement in various pathological conditions. Anti-adenosine deaminase antibody (D-10) serves as an invaluable tool for researchers studying immune responses and related disorders, providing insights into adenosine deaminase function and implications in health and disease.
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adenosine deaminase Antibody (D-10) References:
- The use of adenosine deaminase and adenosine deaminase isoenzymes in the diagnosis of tuberculous pleuritis. | Pérez-Rodriguez, E. and Jiménez Castro, D. 2000. Curr Opin Pulm Med. 6: 259-66. PMID: 10912630
- Neuroprotective effects of adenosine deaminase in the striatum. | Tamura, R., et al. 2016. J Cereb Blood Flow Metab. 36: 709-20. PMID: 26746865
- Adenosine Deaminase Deficiency with a Novel Gene Mutation. | Gupta, M., et al. 2016. Indian J Pediatr. 83: 875-6. PMID: 27086606
- Total adenosine deaminase highly correlated with adenosine deaminase 2 activity in serum. | Gao, ZW., et al. 2022. Ann Rheum Dis. 81: e30. PMID: 32001434
- Urogenital Abnormalities in Adenosine Deaminase Deficiency. | Pajno, R., et al. 2020. J Clin Immunol. 40: 610-618. PMID: 32307643
- Adenosine deaminase - A target for new piperazine derivatives. | Bakaryan, A., et al. 2021. Biophys Chem. 277: 106658. PMID: 34333397
- Adenosine deaminase gene variant in diabetes and obesity. | Dayani, SB., et al. 2022. J Diabetes Metab Disord. 21: 333-338. PMID: 35673471
- Skeletal dysplasia in adenosine deaminase deficiency. | Minagawa, H., et al. 2022. Pediatr Int. 64: e15214. PMID: 35791036
- Updated Management Guidelines for Adenosine Deaminase Deficiency. | Grunebaum, E., et al. 2023. J Allergy Clin Immunol Pract. 11: 1665-1675. PMID: 36736952
- Adenosine deaminase isoenzymes and pleural tuberculosis. | Antony, VB. 1996. J Lab Clin Med. 127: 326-7. PMID: 8656033
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
adenosine deaminase Antibody (D-10) | sc-376889 | 200 µg/ml | $322.00 | |||
adenosine deaminase Antibody (D-10): m-IgG Fc BP-HRP Bundle | sc-540661 | 200 µg Ab; 10 µg BP | $361.00 | |||
adenosine deaminase Antibody (D-10): m-IgG1 BP-HRP Bundle | sc-542278 | 200 µg Ab; 20 µg BP | $361.00 | |||
adenosine deaminase (D-10) Neutralizing Peptide | sc-376889 P | 100 µg/0.5 ml | $69.00 |