Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (73): sc-58598
- Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (73) is a rat monoclonal IgG1 provided at 200 µg/ml
- raised against full length native AChRβ1 of bovine origin
- recommended for detection of the extracellular surface of muscle nicotinic Acetylcholine Receptor β1-subunits of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including bovine
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (73). This work is in progress.
AChRβ1 Antibody (73) is a rat monoclonal IgG1 antibody that detects AChRβ1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). AChRβ1, also known as CHRNB, CMS1D, CMS2A, SCCMS, or CHRNB1, is a 501 amino acid protein that plays a crucial role in the function of nicotinic acetylcholine receptors, which are essential for fast synaptic transmission at the neuromuscular junction. These receptors are composed of five homologous subunits that form a transmembrane aqueous pore, allowing ions to flow in response to acetylcholine binding. The proper functioning of AChRβ1 is vital for muscle contraction and overall neuromuscular function, as defects in the gene encoding this protein can lead to congenital myasthenic syndrome slow-channel type (SCCMS), a condition characterized by muscle weakness affecting various muscle groups, including those responsible for eye movement and facial expressions. Anti-AChRβ1 antibody (73) is an invaluable tool for researchers studying the mechanisms of synaptic transmission and the pathophysiology of neuromuscular disorders, providing insights into the interactions and modifications that influence receptor activity and stability.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (73) | sc-58598 | 200 µg/ml | $322.00 |