Ac-Histone H4 Antibody (F-3): sc-377521
- Ac-Histone H4 Antibody (F-3) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping to a short peptide containing acetylated Serine 1 and Lysine 5, 8 and 12 of Histone H4 of human origin
- recommended for detection of Ser 1, Lys 5, Lys 8 and Lys 12 acetylated Histone H4 of broad species and avian origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for Ac-Histone H4 Antibody (F-3) for WB and IHC(P) applications. These reagents are now offered in bundles with Ac-Histone H4 Antibody (F-3) (see ordering information below).
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Ac-Histone H4 Antibody (F-3) is a mouse monoclonal IgG2b antibody that detects Histone H4 across a broad range of species through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Histone H4 antibody (F-3) specifically recognizes acetylated forms of Histone H4, which plays a crucial role in the regulation of gene expression and chromatin dynamics. Histone H4 is a core component of the nucleosome, where it forms a histone octamer with H2A, H2B, and H3, wrapping approximately 200 base pairs of DNA. This structural arrangement not only compacts DNA into chromatin but also influences the accessibility of transcription factors and other regulatory proteins to DNA, thereby impacting gene transcription. The acetylation of Histone H4, particularly at lysines 5, 8, 12, and 16, is associated with active transcription and chromatin remodeling, making Histone H4 an important marker for studying epigenetic modifications and their effects on cellular processes. Histone H4 monoclonal antibody (F-3) enables researchers to gain insights into the dynamic regulation of gene expression and the role of histone modifications in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ac-Histone H4 Antibody (F-3) | sc-377521 | 200 µg/ml | $322.00 | |||
Ac-Histone H4 Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-540733 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ac-Histone H4 Antibody (F-3): m-IgG2b BP-HRP Bundle | sc-549792 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ac-Histone H4 (F-3) Neutralizing Peptide | sc-377521 P | 100 µg/0.5 ml | $69.00 |