Date published: 2026-5-22

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RAG Antibodies

Santa Cruz Biotechnology features a diverse variety of RAG Antibodies for studying recombination-activating genes (RAG), which play a crucial role in lymphocyte development. RAG monoclonal antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). RAG proteins are essential for the V(D)J recombination process, which generates diverse antigen receptors on B and T lymphocytes, thereby contributing to the adaptive immune response. Proper RAG function is critical for maintaining immune system integrity and preventing immunodeficiencies or lymphoid malignancies. Understanding RAG proteins can provide insights into immune system disorders and potential therapeutic targets. Researchers investigating RAG expression patterns can utilize specific conjugates, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC). Advanced research in immunology depends on reliable detection methods for RAG protein activity and localization. Santa Cruz Biotechnology monoclonal antibodies support groundbreaking immunology research, enabling scientists to uncover new insights into immune system development and function.

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RAG Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

RAG-1 Antibody (D-5)

sc-377127mouse IgM κ727-765 (h)WB, IP, IF, ELISAm, r, h
5
(2)

RAG-2 Antibody (4D5C7)

sc-517209mouse IgG1 κ350-527 (h)WB, IP, ELISAh
1
(2)

RAG CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

RAG-1 CRISPR/Cas9 KO Plasmid (m)

sc-422588mGene KnockoutGFP0
(0)

RAG-1 HDR Plasmid (m)

sc-422588-HDRmHomology Directed RepairPuromycin0
(0)

RAG-2 CRISPR/Cas9 KO Plasmid (m)

sc-422589mGene KnockoutGFP0
(0)

RAG-2 HDR Plasmid (m)

sc-422589-HDRmHomology Directed RepairPuromycin0
(0)

RAG CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

RAG-1 CRISPR Activation Plasmid (h)

sc-401821-ACThGene ActivationPuro, Blast, Hygro0
(0)

RAG siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

RAG-1 siRNA (h)

sc-42962hGene SilencingN/A0
(0)

RAG-1 shRNA Plasmid (h)

sc-42962-SHhGene SilencingPuromycin0
(0)

RAG-1 shRNA (h) Lentiviral Particles

sc-42962-VhGene SilencingPuromycin0
(0)

RAG-1 siRNA (m)

sc-42963mGene SilencingN/A0
(0)

RAG-1 shRNA Plasmid (m)

sc-42963-SHmGene SilencingPuromycin0
(0)

RAG-1 shRNA (m) Lentiviral Particles

sc-42963-VmGene SilencingPuromycin0
(0)

RAG-2 siRNA (h)

sc-36371hGene SilencingN/A0
(0)

RAG-2 shRNA Plasmid (h)

sc-36371-SHhGene SilencingPuromycin0
(0)

RAG-2 shRNA (h) Lentiviral Particles

sc-36371-VhGene SilencingPuromycin0
(0)

RAG-2 siRNA (m)

sc-36372mGene SilencingN/A0
(0)

RAG-2 shRNA Plasmid (m)

sc-36372-SHmGene SilencingPuromycin0
(0)

RAG-2 shRNA (m) Lentiviral Particles

sc-36372-VmGene SilencingPuromycin0
(0)