Date published: 2026-6-4

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MAML Antibodies

Santa Cruz Biotechnology features a diverse variety of MAML Antibodies for investigating Mastermind-like (MAML) proteins in cellular processes. MAML Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MAML proteins function as essential co-activators in the Notch signaling pathway, playing vital roles in cell differentiation, proliferation, and apoptosis. The involvement of MAML proteins in developmental biology and cancer research is particularly significant, as dysregulation of Notch signaling has been linked to various malignancies. Research has shown that MAML proteins interact with multiple transcription factors beyond the Notch pathway, suggesting broader regulatory functions in cell signaling networks. Understanding MAML protein function can reveal potential therapeutic targets for treating diseases associated with aberrant Notch signaling. Investigating MAML proteins may also uncover new mechanisms in embryonic development and tissue homeostasis. Current research indicates that targeting MAML-mediated transcriptional activation could lead to novel therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of MAML proteins and their role in human health and disease.

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MAML Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MAML2 Antibody (G-07)

sc-100778mouse IgG2a κ796-895 (h)WB, IP, ELISAh

new

(3)

MAML3 Antibody (797C2a)

sc-81104mouse IgG1N-Terminal (h)WB, IPh

new

(1)

MAML CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAML2 Double Nickase Plasmid (m)

sc-435408-NICmGene KnockoutPuromycin0
(0)

MAML2 Double Nickase Plasmid (m2)

sc-435408-NIC-2mGene KnockoutPuromycin0
(0)

MAML siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAML2 siRNA (h)

sc-75742hGene SilencingN/A0
(0)

MAML2 shRNA Plasmid (h)

sc-75742-SHhGene SilencingPuromycin0
(0)

MAML2 shRNA (h) Lentiviral Particles

sc-75742-VhGene SilencingPuromycin0
(0)

MAML2 siRNA (m)

sc-75743mGene SilencingN/A0
(0)

MAML2 shRNA Plasmid (m)

sc-75743-SHmGene SilencingPuromycin0
(0)

MAML2 shRNA (m) Lentiviral Particles

sc-75743-VmGene SilencingPuromycin0
(0)

MAML3 siRNA (h)

sc-75744hGene SilencingN/A0
(0)

MAML3 shRNA Plasmid (h)

sc-75744-SHhGene SilencingPuromycin0
(0)

MAML3 shRNA (h) Lentiviral Particles

sc-75744-VhGene SilencingPuromycin0
(0)

MAML3 siRNA (m)

sc-75745mGene SilencingN/A0
(0)

MAML3 shRNA Plasmid (m)

sc-75745-SHmGene SilencingPuromycin0
(0)

MAML3 shRNA (m) Lentiviral Particles

sc-75745-VmGene SilencingPuromycin0
(0)