Date published: 2026-7-12

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GLI Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of GLI Antibodies for investigating the Hedgehog signaling pathway and its implications in various biological processes. Monoclonal GLI Antibodies are suitable for a variety of techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GLI proteins play a crucial role in mediating the effects of Hedgehog signaling, which is essential for cell differentiation, proliferation, and tissue patterning during embryonic development. Dysregulation of GLI proteins has been implicated in several cancers and developmental disorders, making them significant targets for therapeutic intervention and research. Understanding the function and regulation of GLI proteins is vital for advancing our knowledge of developmental biology and disease mechanisms. GLI Antibodies enable researchers to conduct detailed analyses of protein expression, localization, and interactions within cellular pathways. Investigating GLI protein activity helps reveal new insights into developmental processes and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal GLI Antibodies support researchers worldwide in their pursuit of scientific discoveries and medical breakthroughs.

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GLI Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GLI-1/GLI1 Antibody (A-7)

sc-515781mouse IgG1 κ1050-1068 (h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(1)

GLI-1/GLI1 Antibody (C-1)

sc-515751mouse IgG1 κ781-1080 (h)WB, IP, IF, ELISAm, r, h
38
(12)

GLI-2 Antibody (C-10)

sc-271786mouse IgG1 κ841-1140 (h)WB, IP, IF, IHC(P), ELISAm, r, h
56
(14)

GLI-3 Antibody (B-4)

sc-74478mouse IgG2b κ1-280 (h)WB, IP, IF, IHC(P), ELISAm, r, h
5
(6)

GLI siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GLI-2 siRNA (h)

sc-37913hGene SilencingN/A
9
(0)

GLI-2 shRNA Plasmid (h)

sc-37913-SHhGene SilencingPuromycin
9
(0)

GLI-2 shRNA (h) Lentiviral Particles

sc-37913-VhGene SilencingPuromycin
9
(0)

GLI-2 siRNA (m)

sc-145421mGene SilencingN/A0
(0)

GLI-2 shRNA Plasmid (m)

sc-145421-SHmGene SilencingPuromycin0
(0)

GLI-2 shRNA (m) Lentiviral Particles

sc-145421-VmGene SilencingPuromycin0
(0)

GLI-3 siRNA (h)

sc-35483hGene SilencingN/A
1
(0)

GLI-3 shRNA Plasmid (h)

sc-35483-SHhGene SilencingPuromycin
1
(0)

GLI-3 shRNA (h) Lentiviral Particles

sc-35483-VhGene SilencingPuromycin
1
(0)

GLI-3 siRNA (m)

sc-35484mGene SilencingN/A0
(0)

GLI-3 shRNA Plasmid (m)

sc-35484-SHmGene SilencingPuromycin0
(0)

GLI-3 shRNA (m) Lentiviral Particles

sc-35484-VmGene SilencingPuromycin0
(0)

GLI-4 siRNA (h)

sc-75140hGene SilencingN/A0
(0)

GLI-4 shRNA Plasmid (h)

sc-75140-SHhGene SilencingPuromycin0
(0)

GLI-4 shRNA (h) Lentiviral Particles

sc-75140-VhGene SilencingPuromycin0
(0)

GLI-1/GLI1 siRNA (h)

sc-37911hGene SilencingN/A
28
(0)

GLI-1/GLI1 shRNA Plasmid (h)

sc-37911-SHhGene SilencingPuromycin
28
(0)

GLI-1/GLI1 shRNA (h) Lentiviral Particles

sc-37911-VhGene SilencingPuromycin
28
(0)

GLI-1/GLI1 siRNA (m)

sc-37912mGene SilencingN/A
2
(0)

GLI-1/GLI1 shRNA Plasmid (m)

sc-37912-SHmGene SilencingPuromycin
2
(0)

GLI-1/GLI1 shRNA (m) Lentiviral Particles

sc-37912-VmGene SilencingPuromycin
2
(0)

GLI-1/GLI1 siRNA (r)

sc-270268rGene SilencingN/A
1
(0)

GLI-1/GLI1 shRNA Plasmid (r)

sc-270268-SHrGene SilencingPuromycin
1
(0)

GLI-1/GLI1 shRNA (r) Lentiviral Particles

sc-270268-VrGene SilencingPuromycin
1
(0)

GLI CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

GLI-2 CRISPR/Cas9 KO Plasmid (h)

sc-400839Gene Knockouth0
(0)

GLI-2 HDR Plasmid (h)

sc-400839-HDRHomology Directed Repairh0
(0)

GLI-2 CRISPR/Cas9 KO Plasmid (m)

sc-420576Gene Knockoutm0
(0)

GLI-2 HDR Plasmid (m)

sc-420576-HDRHomology Directed Repairm0
(0)

GLI-3 CRISPR/Cas9 KO Plasmid (h)

sc-400853Gene Knockouth0
(0)

GLI-3 HDR Plasmid (h)

sc-400853-HDRHomology Directed Repairh0
(0)

GLI-3 CRISPR/Cas9 KO Plasmid (m)

sc-420577Gene Knockoutm0
(0)

GLI-1/GLI1 CRISPR/Cas9 KO Plasmid (h2)

sc-400266-KO-2Gene Knockouth0
(0)

GLI-1/GLI1 HDR Plasmid (h2)

sc-400266-HDR-2Homology Directed Repairh0
(0)

GLI-1/GLI1 CRISPR/Cas9 KO Plasmid (m)

sc-420575Gene Knockoutm0
(0)

GLI-1/GLI1 HDR Plasmid (m)

sc-420575-HDRHomology Directed Repairm0
(0)

GLI CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

GLI-2 Double Nickase Plasmid (h)

sc-400839-NICGene Knockouth0
(0)

GLI-2 Double Nickase Plasmid (h2)

sc-400839-NIC-2Gene Knockouth0
(0)

GLI-3 Double Nickase Plasmid (h)

sc-400853-NICGene Knockouth0
(0)

GLI-3 Double Nickase Plasmid (h2)

sc-400853-NIC-2Gene Knockouth0
(0)

GLI-1/GLI1 Double Nickase Plasmid (h)

sc-400266-NICGene Knockouth0
(0)

GLI-1/GLI1 Double Nickase Plasmid (h2)

sc-400266-NIC-2Gene Knockouth0
(0)

GLI CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

GLI-2 CRISPR Activation Plasmid (h)

sc-400839-ACTGene Activationh0
(0)

GLI-2 CRISPR Activation Plasmid (m)

sc-420576-ACTGene Activationm0
(0)

GLI-3 CRISPR Activation Plasmid (h)

sc-400853-ACTGene Activationh0
(0)

GLI-1/GLI1 CRISPR Activation Plasmid (h)

sc-400266-ACTGene Activationh0
(0)

GLI-1/GLI1 CRISPR Activation Plasmid (h2)

sc-400266-ACT-2Gene Activationh0
(0)