Cyr61 Inhibitors
Items 11 to 12 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor that can downregulate Cyr61 expression. mTOR signaling can induce Cyr61 expression in certain contexts. By blocking mTOR, Rapamycin can indirectly inhibit Cyr61 and its downstream signaling pathways involved in cell growth, migration, and angiogenesis. Targeting Cyr61 through mTOR inhibition may be relevant in diseases where Cyr61 plays a significant role in tissue remodeling and immune responses. | ||||||
LY2109761 | 700874-71-1 | sc-396262 sc-396262A | 1 mg 5 mg | $89.00 $275.00 | 9 | |
LY2109761 is a selective inhibitor of the TGF-β type I receptor (ALK5) that can block the induction of Cyr61 by TGF-β signaling. By interfering with TGF-β signaling, LY2109761 indirectly downregulates Cyr61 and its downstream effects on cell proliferation, migration, and ECM remodeling. Targeting Cyr61 through TGF-β inhibition may have therapeutic implications in fibrotic disorders, cancer metastasis, and tissue repair, where Cyr61 plays a significant role. | ||||||