Date published: 2025-12-4

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Bis(2,6-diisopropylphenyl)carbodiimide (CAS 2162-74-5)

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CAS Number:
2162-74-5
Molecular Weight:
362.56
Molecular Formula:
C25H34N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bis(2,6-diisopropylphenyl)carbodiimide is used in research related to peptide synthesis and protein cross-linking studies. It serves as a coupling agent in the formation of amide bonds, which is essential for constructing long chains of peptides in a controlled manner. Researchers employ this chemical to explore the efficiency and selectivity of carbodiimide-mediated reactions, particularly in the synthesis of complex biological molecules. Bis(2,6-diisopropylphenyl)carbodiimide is also utilized in studies focusing on the stabilization of proteins and enzymes, where it helps in understanding the structural integrity of these biomolecules under various conditions. Additionally, this compound is involved in the development of new synthetic methodologies that aim to minimize side reactions and improve yield in organic synthesis.


Bis(2,6-diisopropylphenyl)carbodiimide (CAS 2162-74-5) References

  1. The 2-Arsaethynolate Anion: Synthesis and Reactivity Towards Heteroallenes.  |  Hinz, A. and Goicoechea, JM. 2016. Angew Chem Int Ed Engl. 55: 8536-41. PMID: 27093942
  2. Mono- and bimetallic amidinate samarium complexes - synthesis, structure, and hydroamination catalysis.  |  Kazeminejad, N., et al. 2019. Dalton Trans. 48: 8153-8160. PMID: 31070636
  3. Ligands with Two Monoanionic N,N-Binding Sites: Synthesis and Coordination Chemistry.  |  Kretschmer, R. 2020. Chemistry. 26: 2099-2119. PMID: 31755598
  4. The Effect of Surface Treatment with Isocyanate and Aromatic Carbodiimide of Thermally Expanded Vermiculite Used as a Functional Filler for Polylactide-Based Composites.  |  Barczewski, M., et al. 2021. Polymers (Basel). 13: PMID: 33799352
  5. Alkali Metal Complexes of a Bis(diphenylphosphino)methane Functionalized Amidinate Ligand: Synthesis and Luminescence.  |  Zovko, C., et al. 2021. Chemistry. 27: 15119-15126. PMID: 34427374
  6. 3D-Printed Poly (P-Dioxanone) Stent for Endovascular Application: In Vitro Evaluations.  |  Lu, J., et al. 2022. Polymers (Basel). 14: PMID: 35566924
  7. Can Modification with Urethane Derivatives or the Addition of an Anti-Hydrolysis Agent Influence the Hydrolytic Stability of Resin Dental Composite?  |  Szczesio-Wlodarczyk, A., et al. 2023. Int J Mol Sci. 24: PMID: 36901766

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bis(2,6-diisopropylphenyl)carbodiimide, 5 g

sc-484674
5 g
$91.00