3-n-Butylphthalide (CAS 6066-49-5)
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3-n-Butylphthalide is an organic compound that has garnered interest in the field of chemical research due to its interesting properties and potential applications. It is often studied for its role in chemical synthesis, where it acts as a precursor or an intermediate in the production of various complex molecules. In environmental research, 3-n-Butylphthalide is investigated for its ability to influence the degradation of certain pollutants, contributing to the understanding of phthalate metabolism in the environment. Additionally, this compound is used in research focused on understanding the mechanisms of organic compound crystallization, as its structural properties provide a model for studying crystal growth and formation. Research involving 3-n-Butylphthalide also extends to the exploration of its behavior under different physical and chemical conditions, which is important for the design of industrial processes and material science applications.
3-n-Butylphthalide (CAS 6066-49-5) References
- 3-n-Butylphthalide (NBP) reduces apoptosis and enhances vascular endothelial growth factor (VEGF) up-regulation in diabetic rats. | Zhang, T., et al. 2010. Neurol Res. 32: 390-6. PMID: 20483006
- Bioactivation of 3-n-butylphthalide via sulfation of its major metabolite 3-hydroxy-NBP: mediated mainly by sulfotransferase 1A1. | Diao, X., et al. 2014. Drug Metab Dispos. 42: 774-81. PMID: 24468743
- 3-N-butylphthalide improves neuronal morphology after chronic cerebral ischemia. | Zhao, W., et al. 2014. Neural Regen Res. 9: 719-26. PMID: 25206879
- A Review of Recent Advances in Neuroprotective Potential of 3-N-Butylphthalide and Its Derivatives. | Abdoulaye, IA. and Guo, YJ. 2016. Biomed Res Int. 2016: 5012341. PMID: 28053983
- 3-N-Butylphthalide mitigates high glucose-induced injury to Schwann cells: association with nitrosation and apoptosis. | Xu, DD., et al. 2019. Neural Regen Res. 14: 513-518. PMID: 30539821
- 3-N-butylphthalide inhibits neuronal apoptosis in rats with cerebral infarction via targeting P38/MAPK. | Liao, W., et al. 2019. Eur Rev Med Pharmacol Sci. 23: 144-152. PMID: 31389585
- Neuroprotective mechanisms of 3-n-butylphthalide in neurodegenerative diseases. | Luo, R., et al. 2019. Biomed Rep. 11: 235-240. PMID: 31798868
- Novel brain-targeting 3-n-butylphthalide prodrugs for ischemic stroke treatment. | Xiang, H., et al. 2021. J Control Release. 335: 498-514. PMID: 34087248
- 3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells. | Lu, KY., et al. 2021. Biomed Pharmacother. 139: 111687. PMID: 34243611
- Absorption, distribution, metabolism, and excretion of [14C]NBP (3-n-butylphthalide) in rats. | Tian, J., et al. 2021. J Chromatogr B Analyt Technol Biomed Life Sci. 1181: 122915. PMID: 34500404
- Combination of tetrandrine and 3-n-butylphthalide protects against cerebral ischemia-reperfusion injury via ATF2/TLR4 pathway. | Li, C., et al. 2021. Immunopharmacol Immunotoxicol. 43: 749-757. PMID: 34591732
- Efficacy and safety of 3-n-butylphthalide for the treatment of cognitive impairment: A systematic review and meta-analysis. | Zhou, Q., et al. 2022. CNS Neurosci Ther. 28: 1706-1717. PMID: 36047338
- Protective effect of 3-n-butylphthalide against intrastriatal injection of malonic acid-induced neurotoxicity and biochemical alteration in rats. | Yuan, C., et al. 2022. Biomed Pharmacother. 155: 113664. PMID: 36095961
- Advances of neurovascular protective potential of 3-N-butylphthalide and its derivatives in diabetic related diseases. | Tan, SW., et al. 2022. J Diabetes Complications. 36: 108335. PMID: 36240669
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-n-Butylphthalide, 1 g | sc-397256 | 1 g | $505.00 |