Date published: 2025-10-3

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Ternatin (CAS 148619-41-4)

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Application:
Ternatin is an inhibitor of fat accumulation in 3T3-L1 murine adipocytes.
CAS Number:
148619-41-4
Molecular Weight:
738.00
Molecular Formula:
C37H67N7O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ternatin is a novel synthetic compound modeled after naturally occurring substances like terpenes. Various properties of ternatin, such as its actions against microbes, fungi, and its role in cellular defense mechanisms, alongside its interactions in the context of complex neurodegenerative conditions, are under examination. The detailed mechanism by which ternatin operates continues to be an area of active inquiry, as scientists seek to decipher its exact effects on cellular mechanisms.


Ternatin (CAS 148619-41-4) References

  1. Inhibition by the bioflavonoid ternatin of aflatoxin B1-induced lipid peroxidation in rat liver.  |  Souza, MF., et al. 1999. J Pharm Pharmacol. 51: 125-9. PMID: 10217309
  2. Anti-anaphylactic and anti-inflammatory effects of ternatin, a flavonoid isolated from Egletes viscosa Less.  |  Souza, MF., et al. 1992. Braz J Med Biol Res. 25: 1029-32. PMID: 1342824
  3. Ternatin, an anti-inflammatory flavonoid, inhibits thioglycolate-elicited rat peritoneal neutrophil accumulation and LPS-activated nitric oxide production in murine macrophages.  |  Rao, VS., et al. 2003. Planta Med. 69: 851-3. PMID: 14598213
  4. Ternatin, a flavonoid, prevents cyclophosphamide and ifosfamide-induced hemorrhagic cystitis in rats.  |  Vieira, MM., et al. 2004. Phytother Res. 18: 135-41. PMID: 15022166
  5. Importance of the backbone conformation of (-)-ternatin in its fat-accumulation inhibitory activity against 3T3-L1 adipocytes.  |  Shimokawa, K., et al. 2009. Org Biomol Chem. 7: 777-84. PMID: 19194593
  6. (-)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells.  |  Ito, M., et al. 2009. Peptides. 30: 1074-81. PMID: 19463739
  7. Ternatin pretreatment attenuates testicular injury induced by torsion/detorsion in Wistar rats.  |  Guimarães, SB., et al. 2011. Acta Cir Bras. 26: 325-8. PMID: 21808848
  8. Ternatin, a cyclic peptide isolated from mushroom, and its derivative suppress hyperglycemia and hepatic fatty acid synthesis in spontaneously diabetic KK-A(y) mice.  |  Kobayashi, M., et al. 2012. Biochem Biophys Res Commun. 427: 299-304. PMID: 23000156
  9. Inhibition of lipid peroxidation by ternatin, a tetramethoxyflavone from Egletes viscosa L.  |  Souza, MF., et al. 1997. Phytomedicine. 4: 27-31. PMID: 23195242
  10. Effects of bioflavonoid ternatin on liver regeneration and oxidative stress in rats.  |  Melo, JU., et al. 2013. Acta Cir Bras. 28: 435-40. PMID: 23743681
  11. Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex.  |  Carelli, JD., et al. 2015. Elife. 4: PMID: 26651998
  12. Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.  |  Juette, MF., et al. 2022. Elife. 11: PMID: 36264623
  13. Protective effect of ternatin, a flavonoid isolated from Egletes viscosa less., in experimental liver injury.  |  Rao, VS., et al. 1994. Pharmacology. 48: 392-7. PMID: 7914024

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ternatin, 1 mg

sc-391653
1 mg
$321.00