Date published: 2025-11-20

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Fenhexamid (CAS 126833-17-8)

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Alternate Names:
N-(2,3-Dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide
Application:
Fenhexamid is a Hydroxyanilide fungicide.
CAS Number:
126833-17-8
Molecular Weight:
302.20
Molecular Formula:
C14H17Cl2NO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fenhexamid is a fungicide that functions by inhibiting the respiration of fungal cells. It targets the fungal mitochondria, disrupting the electron transport chain and leading to the accumulation of toxic levels of reactive oxygen species within the cells. This disrupts the normal metabolic processes of the fungi, ultimately leading to their death. Fenhexamid′s mechanism of action involves binding to specific sites on the fungal cells, interfering with the production of adenosine triphosphate (ATP) and causing cellular dysfunction.


Fenhexamid (CAS 126833-17-8) References

  1. Processing factors and variability of pyrimethanil, fenhexamid and tolylfluanid in strawberries.  |  Christensen, HB., et al. 2003. Food Addit Contam. 20: 728-41. PMID: 13129790
  2. Photochemical analysis of 14C-fenhexamid in aqueous solution and structural elucidation of a new metabolite.  |  Maheswari, MA., et al. 2010. Chemosphere. 81: 844-52. PMID: 20804999
  3. The sterol biosynthesis inhibitor molecule fenhexamid impacts the vegetative compatibility of Glomus clarum.  |  Cardenas-Flores, A., et al. 2011. Mycorrhiza. 21: 443-449. PMID: 21553021
  4. Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells.  |  Teng, Y., et al. 2013. Toxicol Sci. 131: 71-83. PMID: 23052036
  5. Effect of fenhexamid and cyprodinil on the expression of cell cycle- and metastasis-related genes via an estrogen receptor-dependent pathway in cellular and xenografted ovarian cancer models.  |  Go, RE., et al. 2015. Toxicol Appl Pharmacol. 289: 48-57. PMID: 26344002
  6. The natural fenhexamid-resistant grey mould populations from strawberry in Zhejiang Province are dominated by Botrytis cinerea group S.  |  Yin, D., et al. 2016. Pest Manag Sci. 72: 1540-8. PMID: 26537826
  7. A new transformant selection system for the gray mold fungus Botrytis cinerea based on the expression of fenhexamid-insensitive ERG27 variants.  |  Cohrs, KC., et al. 2017. Fungal Genet Biol. 100: 42-51. PMID: 28188884
  8. Transcriptome and Resistance-Related Genes Analysis of Botrytis cinerea B05.10 Strain to Different Selective Pressures of Cyprodinil and Fenhexamid.  |  Wang, X., et al. 2018. Front Microbiol. 9: 2591. PMID: 30425701
  9. First Report of Fenhexamid-Resistant Botrytis cinerea Causing Gray Mold on Heurchera in a North American Greenhouse.  |  Moorman, GW., et al. 2012. Plant Dis. 96: 147. PMID: 30731886
  10. Activity of Boscalid, Fenhexamid, Fluazinam, Fludioxonil, and Vinclozolin on Growth of Sclerotinia minor and S. sclerotiorum and Development of Lettuce Drop.  |  Matheron, ME. and Porchas, M. 2004. Plant Dis. 88: 665-668. PMID: 30812590
  11. The role of fenhexamid on the proliferation of ovarian cancer BG-1 cells.  |  Fei, A., et al. 2018. Int J Clin Exp Pathol. 11: 2025-2031. PMID: 31938309
  12. The role of fenhexamid on the proliferation of ovarian cancer BG-1 cells [Retraction].  |  . 2020. Int J Clin Exp Pathol. 13: 634. PMID: 32269705
  13. Fenhexamid induces cancer growth and survival via estrogen receptor-dependent and PI3K-dependent pathways in breast cancer models.  |  Go, RE., et al. 2021. Food Chem Toxicol. 149: 112000. PMID: 33484789
  14. A fungicide, fenhexamid, is involved in the migration and angiogenesis in breast cancer cells expressing estrogen receptors.  |  Go, RE., et al. 2022. Life Sci. 305: 120754. PMID: 35780843

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fenhexamid, 100 mg

sc-391482
100 mg
$210.00

Fenhexamid, 500 mg

sc-391482A
500 mg
$370.00

Fenhexamid, 1 g

sc-391482B
1 g
$430.00