Molecular structure of Corynanthine, CAS Number: 483-10-3
Corynanthine (CAS 483-10-3)
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Alternate Names:
Yohimbine; 17α-Hydroxyyohimban-16β-carboxylic acid methyl ester; Methyl (16beta,17alpha)-17-hydroxyyohimban-16-carboxylate
CAS Number:
483-10-3
Molecular Weight:
354.45
Molecular Formula:
C21H26N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Corynanthine, a yohimban alkaloid, is a compound of interest within the realm of analytical chemistry, particularly due to its role as a reference material in qualitative determination processes. Corynanthine is also of interest for its interaction with adrenergic and serotonin receptors in the body. Corynanthine has been studied for its ability to interact with alpha-adrenergic receptors, where it acts as an antagonist. Studies on its biosynthesis, natural function, and ecological role enhance our understanding of chemical ecology and the evolutionary pressures shaping the production of alkaloids in plants.
Corynanthine (CAS 483-10-3) References
- [Comparative toxicity of corynanthine and crystallized corynantheine]. | RAYMOND-HAMET,. 1952. C R Seances Soc Biol Fil. 146: 1042-4. PMID: 13020046
- [Paper partition microchromatography of alkaloids and of various biological nitrogenous bases. III. Examples of the separation of various alkaloids by the acid solvent phase technic (atropine, cocaine, nicotine, sparteine, strychnine and corynanthine families)]. | MUNIER, R. and MACHEBOEUF, M. 1951. Bull Soc Chim Biol (Paris). 33: 846-56. PMID: 14935638
- [Absorption spectra in the ultraviolet of corynanthine and of some of its derivatives]. | JANOT, MM. and GOUTAREL, R. 1949. Ann Pharm Fr. 7: 552-6. PMID: 15407817
- [Studies on predict of absorption of corynanthine, yohimbine, ajmalicine and ajmaline across human intestinal epithelial by using human Caco-2 cells monolayers]. | Ma, L. and Yang, XW. 2008. Zhongguo Zhong Yao Za Zhi. 33: 2373-7. PMID: 19157132
- Endogenous noradrenaline as modulator of hippocampal serotonin (5-HT)-release. Dual effects of yohimbine, rauwolscine and corynanthine as alpha-adrenoceptor antagonists and 5-HT-receptor agonists. | Feuerstein, TJ., et al. 1985. Naunyn Schmiedebergs Arch Pharmacol. 329: 216-21. PMID: 2991775
- [Calcium antagonistic action of corynanthine in isolated guinea pig left atria]. | Cheng, B., et al. 1988. Zhongguo Yao Li Xue Bao. 9: 327-9. PMID: 3195342
- Characterization of alpha-adrenoceptors participating in the central hypotensive and sedative effects of clonidine using yohimbine, rauwolscine and corynanthine. | Timmermans, PB., et al. 1981. Eur J Pharmacol. 70: 7-15. PMID: 6111465
- Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. | Doxey, JC., et al. 1984. Naunyn Schmiedebergs Arch Pharmacol. 325: 136-44. PMID: 6144048
- Corynanthine and aqueous humor dynamics in rabbits and monkeys. | Serle, JB., et al. 1984. Arch Ophthalmol. 102: 1385-8. PMID: 6148057
- Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog. | Shepperson, NB., et al. 1981. J Pharmacol Exp Ther. 219: 540-6. PMID: 6270312
- Effects of yohimbine, rauwolscine and corynanthine on contractions and calcium fluxes induced by depolarization and prostaglandin F2 alpha in rat aorta. | Godfraind, T., et al. 1983. Br J Pharmacol. 80: 115-21. PMID: 6580937
- Corynanthine inhibits, while idazoxan potentiates, cardiotoxic effects of ouabain. | Thomas, GP. 1995. J Auton Pharmacol. 15: 85-91. PMID: 7615577
- Negative inotropic action of corynanthine in the guinea pig papillary muscle is attenuated by glibenclamide. | Kocić, I. 1994. Gen Pharmacol. 25: 553-7. PMID: 7926604
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Corynanthine, 25 mg | sc-363622 | 25 mg | $294.00 |