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sn-Glycero-3-phosphocholine (CAS 28319-77-9)

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Alternate Names:
Choline alfoscerate; Glycerylphosphorylcholine;Cholini alfosceras; L-a-Glycerophosphorylcholine
Application:
sn-Glycero-3-phosphocholine is a nootropic phospholipid
CAS Number:
28319-77-9
Purity:
≥98%
Molecular Weight:
257.2
Molecular Formula:
C8H20NO6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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sn-Glycero-3-phosphocholine, referred to as phosphatidylcholine, is a primary component of biological membranes and is widely used in biochemical and biophysical research. It plays a critical role in membrane dynamics and structure, serving as a model system for studying lipid bilayer behavior and properties. Researchers rely on sn-Glycero-3-phosphocholine to analyze the fluidity and phase transitions of cellular membranes, which are essential for understanding membrane-associated processes such as vesicle formation, fusion, and signaling. Additionally, this compound is a key player in studies on lipid metabolism and the synthesis of liposomes, which are used as drug delivery vehicles and in the design of artificial membranes. Its importance extends to the investigation of membrane proteins, where sn-Glycero-3-phosphocholine-based environments are created to mimic natural conditions for the proper folding and functioning of these proteins. Moreover, its role in cholinergic signaling pathways is investigated to comprehend the biochemical basis of neurotransmission and related cellular functions.


sn-Glycero-3-phosphocholine (CAS 28319-77-9) References

  1. Synthesis of phosphatidylcholine: an improved method without using the cadmium chloride complex of sn-glycero-3-phosphocholine.  |  Ichihara, K., et al. 2005. Chem Phys Lipids. 137: 94-9. PMID: 16054615
  2. A convenient synthesis of phosphatidylcholines: acylation of sn-glycero-3-phosphocholine with fatty acid anhydride and 4-pyrrolidinopyridine.  |  Patel, KM., et al. 1979. J Lipid Res. 20: 674-7. PMID: 490045

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

sn-Glycero-3-phosphocholine, 5 g

sc-301813
5 g
$112.00

sn-Glycero-3-phosphocholine, 25 g

sc-301813A
25 g
$281.00

Do you have it in stock? How long will it take to ship if I order?

Asked by: eunjin
Thank you for your question. Please contact one of our authorized distributors for information about current product availability and shipping lead times.
Answered by: Technical Support
Date published: 2019-01-25

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. sn-Glycero-3-phosphocholine, sc-301813, is a white powder.
Answered by: TechService7
Date published: 2017-02-15
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Rated 5 out of 5 by from BangBang, HJ. et al. (PubMed 26212962) attempted to optimize the preparation of sn-Glycero-3-phosphocholine, a nootropic phospholipid, via phospholipase A1-catalyzed hydrolysis of soy phosphatidylcholine. -SCBT Publication Review
Date published: 2015-04-26
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sn-Glycero-3-phosphocholine is rated 5.0 out of 5 by 1.
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