Date published: 2025-10-19

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Guanosine-5′-monophosphate (CAS 85-32-5)

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Alternate Names:
5′-GMP; Guanosine 5′-monophosphoric acid
Application:
Guanosine-5′-monophosphate is a guanine nucleotide
CAS Number:
85-32-5
Purity:
≥97%
Molecular Weight:
363.22
Molecular Formula:
C10H14N5O8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Guanosine-5′-monophosphate (GMP) is a guanine nucleotide containing one phosphate group esterified to the sugar moiety. A nucleotide, it holds significance in cellular metabolism, participating in numerous biochemical processes. Serving as an intermediate in nucleic acid and protein synthesis, Guanosine-5′-monophosphate has an essential role in regulating various cellular activities, including energy production, cell growth, and differentiation. Additionally, Guanosine-5′-monophosphate acts as a key component in gene expression. It is employed in the exploration of cellular metabolism, gene expression, enzyme kinetics, and metabolic pathway regulation.


Guanosine-5′-monophosphate (CAS 85-32-5) References

  1. Complexation of antimony (Sb(V)) with guanosine 5'-monophosphate and guanosine 5'-diphospho-D-mannose: formation of both mono- and bis-adducts.  |  Chai, Y., et al. 2005. J Inorg Biochem. 99: 2257-63. PMID: 16214217
  2. Chlorine dioxide oxidation of guanosine 5'-monophosphate.  |  Napolitano, MJ., et al. 2006. Chem Res Toxicol. 19: 1451-8. PMID: 17112232
  3. Guanosine-5'-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition.  |  Molz, S., et al. 2009. Neurochem Int. 55: 703-9. PMID: 19576258
  4. A bulky platinum triamine complex that reacts faster with guanosine 5'-monophosphate than with N-acetylmethionine.  |  Sandlin, RD., et al. 2010. J Inorg Biochem. 104: 214-6. PMID: 19906431
  5. Ag(+)-mediated assembly of 5'-guanosine monophosphate.  |  Loo, K., et al. 2010. J Phys Chem B. 114: 4320-6. PMID: 20205377
  6. Circular dichroism study of supramolecular assemblies of guanosine 5'-monophosphate.  |  Panda, M. and Walmsley, JA. 2011. J Phys Chem B. 115: 6377-83. PMID: 21500778
  7. Guanosine 5'-monophosphate-chelated calcium and iron feed additives maintains egg production and prevents Salmonella Gallinarum in experimentally infected layers.  |  Noh, HJ., et al. 2017. J Vet Sci. 18: 291-297. PMID: 28057911
  8. Ultrafast Nuclear Dynamics of Photoexcited Guanosine-5'-Monophosphate in Three Singlet States.  |  Mondal, S. and Puranik, M. 2017. J Phys Chem B. 121: 7095-7107. PMID: 28653848
  9. A novel non-enzymatic sensing platform for determination of 5'-guanosine monophosphate in meat.  |  Fei, Q., et al. 2019. Food Chem. 286: 515-521. PMID: 30827641
  10. An efficient synthesis of 3'-O-triazole modified guanosine-5'-O-monophosphate using click chemistry.  |  Senthilvelan, A., et al. 2019. Nucleosides Nucleotides Nucleic Acids. 38: 418-427. PMID: 30938235
  11. Excited state dynamics of 7-deazaguanosine and guanosine 5'-monophosphate.  |  Krul, SE., et al. 2021. J Chem Phys. 154: 075103. PMID: 33607894
  12. The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-β-synthase domain.  |  Knejzlík, Z., et al. 2022. FEBS J. 289: 5571-5598. PMID: 35338694
  13. Adsorption separation of guanosine 5'-Monophosphate and cytidine 5'-Monophosphate by mixed-mode Resin HD-1: Experimental study and mathematical modeling.  |  Jiao, P., et al. 2022. J Chromatogr A. 1678: 463359. PMID: 35914411
  14. Conformation, hydrogen bonding and aggregate formation of guanosine 5'-monophosphate and guanosine in dimethylsulfoxide.  |  West, RT., et al. 1994. Nucleic Acids Res. 22: 5128-34. PMID: 7800509
  15. Responses to monosodium glutamate and guanosine 5'-monophosphate in rat fungiform taste cells.  |  Lin, W. and Kinnamon, SC. 1998. Ann N Y Acad Sci. 855: 407-11. PMID: 9929633

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Guanosine-5′-monophosphate, 1 g

sc-295032
1 g
$316.00

Guanosine-5′-monophosphate, 2.5 g

sc-295032A
2.5 g
$622.00

Guanosine-5′-monophosphate, 5 g

sc-295032B
5 g
$1030.00