Molecular structure of Pristane, CAS Number: 1921-70-6
Pristane (CAS 1921-70-6)
Alternate Names:
Pristane is also known as 2,6,10,14-Tetramethylpentadecane.
Application:
Pristane is a hydrocarbon oil adjuvant widely used to induce tumorgenesis in mice and arthritis and lupus nephritis in rats.
CAS Number:
1921-70-6
Purity:
≥95%
Molecular Weight:
268.52
Molecular Formula:
C19H40
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Pristane is a hydrocarbon oil adjuvant widely used to induce tumorgenesis in mice and arthritis and lupus nephritis in rats. In BALB/c strain mice, Pristane led to myeloma development when used as an inflammation-inducing agent. In rats, Pristane has been utilized as a rheumatoid arthritis-inducing agent. Additionally, it can work as an adjuvant in the generation of monoclonal antibodies in mouse ascites.
Pristane (CAS 1921-70-6) References
- Widespread susceptibility among inbred mouse strains to the induction of lupus autoantibodies by pristane. | Satoh, M., et al. 2000. Clin Exp Immunol. 121: 399-405. PMID: 10931159
- Mouse plasmacytoma: an experimental model of human multiple myeloma. | Gadó, K., et al. 2001. Haematologica. 86: 227-36. PMID: 11255268
- Interferon-gamma is required for lupus nephritis in mice treated with the hydrocarbon oil pristane. | Richards, HB., et al. 2001. Kidney Int. 60: 2173-80. PMID: 11737591
- Arthritis induced in rats with nonimmunogenic adjuvants as models for rheumatoid arthritis. | Holmdahl, R., et al. 2001. Immunol Rev. 184: 184-202. PMID: 12086312
- Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis. | Savarese, E., et al. 2008. Arthritis Rheum. 58: 1107-15. PMID: 18383384
- Induction of autoimmunity by pristane and other naturally occurring hydrocarbons. | Reeves, WH., et al. 2009. Trends Immunol. 30: 455-64. PMID: 19699150
- Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats. | Meng, L., et al. 2010. Arthritis Res Ther. 12: R103. PMID: 20500834
- Toll-like receptor 2 is required for autoantibody production and development of renal disease in pristane-induced lupus. | Urbonaviciute, V., et al. 2013. Arthritis Rheum. 65: 1612-23. PMID: 23450347
- MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats. | Jiang, C., et al. 2014. Arthritis Res Ther. 16: R9. PMID: 24423102
- Pristane-induced lupus: considerations on this experimental model. | Freitas, EC., et al. 2017. Clin Rheumatol. 36: 2403-2414. PMID: 28879482
- Nonrandom chromosome changes involving the Ig gene-carrying chromosomes 12 and 6 in pristane-induced mouse plasmacytomas. | Ohno, S., et al. 1979. Cell. 18: 1001-7. PMID: 519762
- Anti-nuclear antibody production and immune-complex glomerulonephritis in BALB/c mice treated with pristane. | Satoh, M., et al. 1995. Proc Natl Acad Sci U S A. 92: 10934-8. PMID: 7479913
- Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane. | Satoh, M. and Reeves, WH. 1994. J Exp Med. 180: 2341-6. PMID: 7964507
- Pristane-induced arthritis in rats: a new model for rheumatoid arthritis with a chronic disease course influenced by both major histocompatibility complex and non-major histocompatibility complex genes. | Vingsbo, C., et al. 1996. Am J Pathol. 149: 1675-83. PMID: 8909256
- Interleukin 6 dependence of anti-DNA antibody production: evidence for two pathways of autoantibody formation in pristane-induced lupus. | Richards, HB., et al. 1998. J Exp Med. 188: 985-90. PMID: 9730900
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pristane, 100 ml | sc-281684 | 100 ml | $566.00 | |||
Pristane, 250 ml | sc-281684A | 250 ml | $1126.00 |