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Sucrose monolaurate (CAS 25339-99-5)

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Alternate Names:
n-Monododecanoate-a-D-glucopyranoside; Sucrose monolaurate
Application:
Sucrose monolaurate is a non-ionic detergent used to solubilize membrane bound proteins
CAS Number:
25339-99-5
Molecular Weight:
524.60
Molecular Formula:
C24H44O12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sucrose monolaurate is an ester of sucrose and lauric acid that is explored in research for its surfactant properties, which can affect the solubilization and stability of various compounds. In food science, it is studied for its ability to alter the texture and preservation of food products due to its interaction with lipid components. In the field of microbiology, sucrose monolaurate is examined for its impact on microbial cell walls and membranes, providing insights into the mechanisms that influence microbial growth and survival. Additionally, researchers utilize this compound in the study of biofilms, where its role in affecting the integrity and dispersion of the biofilm matrix can be critical in controlling biofilm development on various surfaces.


Sucrose monolaurate (CAS 25339-99-5) References

  1. Inhibitory effects of sucrose fatty acid esters on survival of Yersinia enterocolitica on eggshell surface and use of blue lake as indicator of bacterial penetration into eggs.  |  Favier, GI., et al. 2009. J Appl Microbiol. 106: 774-83. PMID: 19191962
  2. Emulsification mechanism and storage instabilities of hydrocarbon-in-water sub-micron emulsions stabilised with Tweens (20 and 80), Brij 96v and sucrose monoesters.  |  Henry, JV., et al. 2009. J Colloid Interface Sci. 338: 201-6. PMID: 19589533
  3. Sucrose monolaurate improves the efficacy of sodium hypochlorite against Escherichia coli O157:H7 on spinach.  |  Xiao, D., et al. 2011. Int J Food Microbiol. 145: 64-8. PMID: 21168229
  4. Sucrose monolaurate synthesis with Protex 6L immobilized on electrospun TiO2 nanofiber.  |  Wang, XR., et al. 2011. Biotechnol Lett. 33: 1831-5. PMID: 21544616
  5. In vitro-in vivo study of CoQ10-loaded lipid nanoparticles in comparison with nanocrystals.  |  Piao, H., et al. 2011. Int J Pharm. 419: 255-9. PMID: 21803142
  6. Effect of lactose monolaurate on pathogenic and nonpathogenic bacteria.  |  Wagh, A., et al. 2012. Appl Environ Microbiol. 78: 3465-8. PMID: 22344640
  7. Solubilization of simvastatin and phytosterols in a dilutable microemulsion system.  |  Fisher, S., et al. 2013. Colloids Surf B Biointerfaces. 107: 35-42. PMID: 23466540
  8. Characterization of enzymatically prepared sugar medium-chain fatty acid monoesters.  |  Zhang, X., et al. 2015. J Sci Food Agric. 95: 1631-7. PMID: 25103468
  9. Lipase-Catalyzed Synthesis of Sucrose Monolaurate and Its Antibacterial Property and Mode of Action against Four Pathogenic Bacteria.  |  Shao, SY., et al. 2018. Molecules. 23: PMID: 29738519
  10. Effect of Vitamin E and a Long-Chain Alcohol n-Octanol on the Carbohydrate-Based Nonionic Amphiphile Sucrose Monolaurate-Formulation of Newly Developed Niosomes and Application in Cell Imaging.  |  Roy, A., et al. 2017. ACS Omega. 2: 7637-7646. PMID: 30023559
  11. Non-ionic surfactants as innovative skin penetration enhancers: insight in the mechanism of interaction with simple 2D stratum corneum model system.  |  Strati, F., et al. 2021. Eur J Pharm Sci. 157: 105620. PMID: 33122012
  12. Interactions between poloxamer, PEOx-PPOy-PEOx, and non-ionic surfactant, sucrose monolaurate: A study on potential allergenic effect using model phospholipid membrane.  |  Kwek, JW., et al. 2022. Colloids Surf B Biointerfaces. 209: 112153. PMID: 34673306
  13. In Silico-Based Experiments on Mechanistic Interactions between Several Intestinal Permeation Enhancers with a Lipid Bilayer Model.  |  Kneiszl, R., et al. 2022. Mol Pharm. 19: 124-137. PMID: 34913341
  14. Effect of Spontaneous and Water-Based Passivation on Components and Parameters of Ti6Al4V (ELI Grade) Surface Tension and Its Wettability by an Aqueous Solution of Sucrose Ester Surfactants.  |  Krawczyk, J., et al. 2021. Molecules. 27: PMID: 35011408
  15. Integration of Trehalose Lipids with Dissociative Trehalose Enables Cryopreservation of Human RBCs.  |  Wang, Y., et al. 2023. ACS Biomater Sci Eng. 9: 498-507. PMID: 36577138
  16. Diameters of bronchi at asymmetrical divisions.  |  Hooper, G. 1977. Respir Physiol. 31: 291-4. PMID: 609847
  17. Detergents for extraction of visual pigments: types, solubilization, and stability.  |  Fong, SL., et al. 1982. Methods Enzymol. 81: 133-40. PMID: 6980357
  18. Solubilization and characterization of atrial muscarinic acetylcholine receptors in sucrose monolaurate.  |  Rinken, A. and Haga, T. 1993. Arch Biochem Biophys. 301: 158-64. PMID: 8442658
  19. Inhibitory effects of sucrose monolaurate, alone and in combination with organic acids, on Listeria monocytogenes and Staphylococcus aureus.  |  Monk, JD., et al. 1996. J Appl Bacteriol. 81: 7-18. PMID: 8675484

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sucrose monolaurate, 500 mg

sc-281160
500 mg
$270.00

Sucrose monolaurate, 1 g

sc-281160A
1 g
$310.00

Sucrose monolaurate, 5 g

sc-281160B
5 g
$650.00

Sucrose monolaurate, 10 g

sc-281160C
10 g
$1200.00

can you provide COA of Sucrose monolaurate (CAS 25339-99-5)?

Asked by: Cathy
Thank you for your question. Here is a previous COA : https://datasheets.scbt.com/coa/coa.php?sc=sc-281160B&lot=D0320
Answered by: BlakeJ
Date published: 2024-01-11
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Rated 5 out of 5 by from Monk et alMonk et al. (PubMed ID 8675484) found that sucrose monolaurate was lethal to Listeria monocytes.
Date published: 2015-05-07
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Sucrose monolaurate is rated 5.0 out of 5 by 1.
  • y_2025, m_10, d_14, h_6
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