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Patchouli alcohol (CAS 5986-55-0)

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Application:
Patchouli alcohol is a sesquiterpene alcohol found in patchouli oil
CAS Number:
5986-55-0
Purity:
≥98%
Molecular Weight:
222.37
Molecular Formula:
C15H26O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Patchouli alcohol (PA) is a volatile monoterpene alcohol obtained from the essential oil of the plant Pogostemon cablin, referred to as patchouli. This naturally occurring compound possesses a delightful aroma, making it a sought-after ingredient in perfumes, cosmetics, and aromatherapy. While the precise mechanism of action of Patchouli alcohol remains under investigation, it is hypothesized that it operates by regulating the expression of diverse genes and proteins involved in processes such as inflammation, apoptosis, and cell cycle regulation.


Patchouli alcohol (CAS 5986-55-0) References

  1. Patchouli alcohol activates PXR and suppresses the NF-κB-mediated intestinal inflammatory.  |  Zhang, G., et al. 2020. J Ethnopharmacol. 248: 112302. PMID: 31614203
  2. Patchouli Alcohol, a Compound from Pogostemon cablin, Inhibits Obesity.  |  Lee, J., et al. 2020. J Med Food. 23: 326-334. PMID: 31750759
  3. Potential benefits of patchouli alcohol in prevention of human diseases: A mechanistic review.  |  Lee, HS., et al. 2020. Int Immunopharmacol. 89: 107056. PMID: 33039955
  4. Patchouli Alcohol Modulates the Pregnancy X Receptor/Toll-like Receptor 4/Nuclear Factor Kappa B Axis to Suppress Osteoclastogenesis.  |  Lu, Q., et al. 2021. Front Pharmacol. 12: 684976. PMID: 34177594
  5. Patchouli alcohol ameliorates acute liver injury via inhibiting oxidative stress and gut-origin LPS leakage in rats.  |  Xu, L., et al. 2021. Int Immunopharmacol. 98: 107897. PMID: 34182243
  6. Patchouli alcohol ameliorates skeletal muscle insulin resistance and NAFLD via AMPK/SIRT1-mediated suppression of inflammation.  |  Pyun, DH., et al. 2021. Mol Cell Endocrinol. 538: 111464. PMID: 34601002
  7. Patchouli alcohol as a selective estrogen receptor β agonist ameliorates AD-like pathology of APP/PS1 model mice.  |  Yan, QY., et al. 2022. Acta Pharmacol Sin. 43: 2226-2241. PMID: 35091686
  8. Patchouli alcohol suppresses castration-resistant prostate cancer progression by inhibiting NF-κB signal pathways.  |  Cai, J., et al. 2022. Transl Androl Urol. 11: 528-542. PMID: 35558260
  9. Patchouli alcohol protects against myocardial ischaemia-reperfusion injury by regulating the Notch1/Hes1 pathway.  |  Lu, Y., et al. 2022. Pharm Biol. 60: 949-957. PMID: 35588098
  10. Patchouli Alcohol Inhibits D-Gal Induced Oxidative Stress and Ameliorates the Quality of Aging Cartilage via Activating the Nrf2/HO-1 Pathway in Mice.  |  Chen, M., et al. 2022. Oxid Med Cell Longev. 2022: 6821170. PMID: 35720186
  11. Patchouli alcohol ameliorates the learning and memory impairments in an animal model of Alzheimer's disease via modulating SIRT1.  |  Xu, QQ., et al. 2022. Phytomedicine. 106: 154441. PMID: 36108371
  12. Patchouli alcohol improved diarrhea-predominant irritable bowel syndrome by regulating excitatory neurotransmission in the myenteric plexus of rats.  |  Chen, W., et al. 2022. Front Pharmacol. 13: 943119. PMID: 36452228
  13. Patchouli alcohol inhibits GPBAR1-mediated cell proliferation, apoptosis, migration, and invasion in prostate cancer.  |  Cai, J., et al. 2022. Transl Androl Urol. 11: 1555-1567. PMID: 36507482

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Patchouli alcohol, 10 mg

sc-281124
10 mg
$82.00

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Date published: 2018-08-29
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Rated 5 out of 5 by from Worked fine in our experimentsWorked fine in our experiments.
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Patchouli alcohol is rated 5.0 out of 5 by 1.
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