Beauvericin (CAS 26048-05-5)
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Beauvericin, a cyclic hexadecane dipeptide present in certain fungi, including Beauveria species, has attracted the interest of researchers in the fields of mycology and biochemistry. It has been studied for its ionophore properties, which allow it to form complexes with cations (especially calcium ions) and facilitate their passage through lipid membranes. This unique ability makes beauvericin a topic of investigation in cellular research, where understanding ion gradients and disruption of homeostasis is crucial. In agricultural research, the role of beauvericin as a natural insecticidal compound has been studied for potential applications in pest management, focusing on its effects on insect physiology and its specificity. Furthermore, its biological activity is of interest for elucidating the mechanism of action at the molecular level, which may inform the development of new bioactive compounds. This compound is also a reference point for the study of fungal secondary metabolites, contributing to our understanding of fungal ecology, evolution, and interactions between fungi and other organisms.
Beauvericin (CAS 26048-05-5) References
- The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis. | Tonshin, AA., et al. 2010. Toxicology. 276: 49-57. PMID: 20621153
- Multi-residue screening method to quantify mycotoxins in aqueous environmental samples. | Schenzel, J., et al. 2010. J Agric Food Chem. 58: 11207-17. PMID: 20925381
- Beauvericin induced erythrocyte cell membrane scrambling. | Qadri, SM., et al. 2011. Toxicology. 283: 24-31. PMID: 21296643
- Beauvericin inhibits melanogenesis by regulating cAMP/PKA/CREB and LXR-α/p38 MAPK-mediated pathways. | Lee, SE., et al. 2018. Sci Rep. 8: 14958. PMID: 30297846
- In Vitro Activity of Beauvericin against All Developmental Stages of Sarcoptes scabiei. | Al Khoury, C., et al. 2020. Antimicrob Agents Chemother. 64: PMID: 32122897
- Divergence of Beauvericin Synthase Gene among Fusarium and Trichoderma Species. | Urbaniak, M., et al. 2020. J Fungi (Basel). 6: PMID: 33203083
- Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods. | Al Khoury, C., et al. 2021. Sci Rep. 11: 10865. PMID: 34035330
- The regulation of BbLaeA on the production of beauvericin and bassiatin in Beauveria bassiana. | Yin, M., et al. 2021. World J Microbiol Biotechnol. 38: 1. PMID: 34817662
- In silico evidence of beauvericin antiviral activity against SARS-CoV-2. | Al Khoury, C., et al. 2022. Comput Biol Med. 141: 105171. PMID: 34968860
- Beauvericin (BEA) and enniatin B (ENNB)-induced impairment of mitochondria and lysosomes - Potential sources of intracellular reactive iron triggering ferroptosis in Atlantic salmon primary hepatocytes. | Søderstrøm, S., et al. 2022. Food Chem Toxicol. 161: 112819. PMID: 35038498
- The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway. | Yang, X., et al. 2022. Front Immunol. 13: 856230. PMID: 35464417
- Improvement of beauvericin production by Fusarium oxysporum AB2 under solid-state fermentation using an optimised liquid medium and co-cultures. | Vásquez-Bonilla, JN., et al. 2022. Mycotoxin Res. 38: 175-183. PMID: 35501595
- Study on In Vitro Metabolism and In Vivo Pharmacokinetics of Beauvericin. | Yuan, Y., et al. 2022. Toxins (Basel). 14: PMID: 35878215
- Multigene Phylogeny, Beauvericin Production and Bioactive Potential of Fusarium Strains Isolated in India. | Rana, S., et al. 2022. J Fungi (Basel). 8: PMID: 35887419
- Interaction of the Emerging Mycotoxins Beauvericin, Cyclopiazonic Acid, and Sterigmatocystin with Human Serum Albumin. | Fliszár-Nyúl, E., et al. 2022. Biomolecules. 12: PMID: 36009000
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Beauvericin, 1 mg | sc-280609 | 1 mg | $75.00 | |||
Beauvericin, 5 mg | sc-280609A | 5 mg | $210.00 |