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3-Hydroxyhexanoic acid (CAS 10191-24-9)

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Alternate Names:
3-Hydroxy C6:0 fatty acid
CAS Number:
10191-24-9
Molecular Weight:
132
Molecular Formula:
C6H12O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Hydroxyhexanoic acid is a chemical compound that plays a significant role in various research applications, especially in the field of polymer science. It is used in the synthesis of polyhydroxyalkanoates (PHAs), which are biodegradable polymers studied for their potential as environmentally friendly plastics. In biochemical research, 3-hydroxyhexanoic acid serves as a monomer in the study of metabolic pathways and enzyme kinetics involved in the production of PHAs by microorganisms. Researchers also employ this compound to better understand fatty acid metabolism, as 3-hydroxyhexanoic acid is an intermediate in the omega-oxidation pathway of fatty acids. Moreover, it is involved in studies related to the biosynthesis of natural products, as certain microorganisms can produce 3-hydroxyhexanoic acid as a metabolic byproduct, which contributes to the understanding of their ecological roles and interactions.


3-Hydroxyhexanoic acid (CAS 10191-24-9) References

  1. Production of polyhydroxyalkanoic acids by Ralstonia eutropha and Pseudomonas oleovorans from an oil remaining from biotechnological rhamnose production.  |  Füchtenbusch, B., et al. 2000. Appl Microbiol Biotechnol. 53: 167-72. PMID: 10709978
  2. Accumulation of Poly[(R)-3-hydroxyalkanoates] in Pseudomonas oleovorans during growth with octanoate in continuous culture at different dilution rates.  |  Durner, R., et al. 2000. Appl Environ Microbiol. 66: 3408-14. PMID: 10919799
  3. Development of a process for the biotechnological large-scale production of 4-hydroxyvalerate-containing polyesters and characterization of their physical and mechanical properties.  |  Gorenflo, V., et al. 2001. Biomacromolecules. 2: 45-57. PMID: 11749154
  4. Bacterial poly(hydroxyalkanoates) as a source of chiral hydroxyalkanoic acids.  |  Ren, Q., et al. 2005. Biomacromolecules. 6: 2290-8. PMID: 16004474
  5. Biosynthesis of medium chain length poly(3-hydroxyalkanoates) (mcl-PHAs) by Comamonas testosteroni during cultivation on vegetable oils.  |  Thakor, N., et al. 2005. Bioresour Technol. 96: 1843-50. PMID: 16084364
  6. Microbial production of medium-chain-length 3-hydroxyalkanoic acids by recombinant Pseudomonas putida KT2442 harboring genes fadL, fadD and phaZ.  |  Yuan, MQ., et al. 2008. FEMS Microbiol Lett. 283: 167-75. PMID: 18422622
  7. Urinary 3-hydroxydicarboxylic acids in pathophysiology of metabolic disorders with dicarboxylic aciduria.  |  Tserng, KY., et al. 1991. Metabolism. 40: 676-82. PMID: 1870421
  8. Medium- and long-chain 3-hydroxymonocarboxylic acids: analysis by gas chromatography combined with mass spectrometry.  |  Dorland, L., et al. 1991. Biomed Chromatogr. 5: 161-4. PMID: 1912723
  9. Metabolic origin of urinary 3-hydroxy dicarboxylic acids.  |  Tserng, KY. and Jin, SJ. 1991. Biochemistry. 30: 2508-14. PMID: 2001377
  10. Genetic replacement of tesB with PTE1 affects chain-length proportions of 3-hydroxyalkanoic acids produced through β-oxidation of oleic acid in Escherichia coli.  |  Seto, Y., et al. 2010. J Biosci Bioeng. 110: 392-6. PMID: 20547355
  11. Microparticles prepared from biodegradable polyhydroxyalkanoates as matrix for encapsulation of cytostatic drug.  |  Murueva, AV., et al. 2013. J Mater Sci Mater Med. 24: 1905-15. PMID: 23674057
  12. Japan Flavour and Fragrance Materials Association's (JFFMA) safety assessment of food-flavouring substances uniquely used in Japan that belong to the class of aliphatic primary alcohols, aldehydes, carboxylic acids, acetals and esters containing additional oxygenated functional groups.  |  Saito, K., et al. 2017. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 34: 1474-1484. PMID: 28540764
  13. SUPERSEDED: Safety assessment of the substance poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate) for use in food contact materials.  |  , ., et al. 2018. EFSA J. 16: e05326. PMID: 32625967
  14. Three new O-isocrotonyl-3-hydroxybutyric acid congeners produced by a sea anemone-derived marine bacterium of the genus Vibrio.  |  Li, D., et al. 2020. Beilstein J Org Chem. 16: 1869-1874. PMID: 32802204
  15. Ornibactins--a new family of siderophores from Pseudomonas.  |  Stephan, H., et al. 1993. Biometals. 6: 93-100. PMID: 7689374

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Hydroxyhexanoic acid, 25 mg

sc-280368
25 mg
$277.00