Date published: 2025-10-21

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1,6-Hexanedithiol (CAS 1191-43-1)

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Alternate Names:
1,6-Dimercaptohexane; Hexamethylene dimercaptan
Application:
1,6-Hexanedithiol is used in self-assembled monolayers (SAMs)
CAS Number:
1191-43-1
Molecular Weight:
150.31
Molecular Formula:
C6H14S2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,6-Hexanedithiol is a chemical compound that functions as a cross-linking agent in polymer chemistry. It acts by forming covalent bonds between polymer chains, leading to the creation of a three-dimensional network structure. This cross-linking process enhances the mechanical strength, thermal stability, and chemical resistance of the polymer material. At the molecular level, 1,6-Hexanedithiol interacts with the polymer chains through thiol groups, facilitating the formation of strong and durable bonds. 1,6-Hexanedithiol′s mechanism of action involves the promotion of polymer cross-linking, which is for the development of advanced materials with improved properties. In the context of research and development, 1,6-Hexanedithiol plays a significant role in the modification and enhancement of polymer materials, contributing to the advancement of various industrial and technological applications.


1,6-Hexanedithiol (CAS 1191-43-1) References

  1. In-situ analysis of stepwise self-assembled 1,6-hexanedithiol multilayers by surface plasmon resonance measurements.  |  Chah, S., et al. 2002. Chem Commun (Camb). 2094-5. PMID: 12357794
  2. Copolymeric polythioesters by lipase-catalyzed thioesterification and transthioesterification of alpha,omega-alkanedithiols.  |  Weber, N., et al. 2006. Appl Microbiol Biotechnol. 70: 290-7. PMID: 16007456
  3. 1,6-Hexanedithiol monolayer as a receptor for specific recognition of alkylmercury.  |  Ji, HF., et al. 2005. Analyst. 130: 1577-9. PMID: 16284654
  4. Measurements of stretch lengths of gold mono-atomic wires covered with 1,6-hexanedithiol in 0.1 M NaClO4 with an electrochemical scanning tunneling microscope.  |  Sun, J., et al. 2008. Ultramicroscopy. 108: 1034-9. PMID: 18565671
  5. Accurate determination of multiple sets of single molecular conductance of Au/1,6-hexanedithiol/Au break junctions by ultra-high vacuum-scanning tunneling microscope and analyses of individual current-separation curves.  |  Nishikawa, A., et al. 2007. Nanotechnology. 18: 424005. PMID: 21730438
  6. Facile Synthesis of Resveratrol Nanogels with Enhanced Fluorescent Emission.  |  Chen, X., et al. 2019. Macromol Biosci. 19: e1800438. PMID: 30516341
  7. Gold Nanoparticle Self-Aggregation on Surface with 1,6-Hexanedithiol Functionalization.  |  Stetsenko, M., et al. 2020. Nanomaterials (Basel). 10: PMID: 32168942
  8. Dual DNA Transfection Using 1,6-Hexanedithiol-Conjugated Maleimide-Functionalized PU-PEI600 For Gene Correction in a Patient iPSC-Derived Fabry Cardiomyopathy Model.  |  Chien, CS., et al. 2021. Front Cell Dev Biol. 9: 634190. PMID: 34422789
  9. Genetically Modified Soybean Detection Using a Biosensor Electrode with a Self-Assembled Monolayer of Gold Nanoparticles.  |  Chou, CC., et al. 2022. Biosensors (Basel). 12: PMID: 35448267
  10. Point-of-Care Based Electrochemical Immunoassay for Epstein-Barr Virus Detection.  |  Yu, M., et al. 2022. J Anal Methods Chem. 2022: 5711384. PMID: 35677726
  11. Cross-Linked Networks of 1,6-Hexanedithiol with Gold Nanoparticles to Improve Permeation Flux of Polyethersulfone Membrane.  |  Niu, X., et al. 2022. Membranes (Basel). 12: PMID: 36557114
  12. Enhanced charge transport across molecule-nanoparticle-molecule sandwiches.  |  Zhou, P., et al. 2023. Phys Chem Chem Phys. 25: 7176-7183. PMID: 36810584
  13. Magnetoresistance originated from the Au/S interface in Au/1,6-hexanedithiol/Au single-molecule junctions at room temperature.  |  Andika, R., et al. 2023. Phys Chem Chem Phys. 25: 18642-18645. PMID: 37408499

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,6-Hexanedithiol, 5 g

sc-280254
5 g
$46.00