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vitamin e nicotinate (CAS 43119-47-7)

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Alternate Names:
alpha-tocopheryl nicotinate
CAS Number:
43119-47-7
Purity:
≥98%
Molecular Weight:
535.80
Molecular Formula:
C35H53NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Vitamin E nicotinate is studied for its antioxidant properties, which are particularly relevant in the context of protecting cellular components from oxidative damage. In the field of molecular biology, it is used to investigate the protective effects on nucleic acids and to understand the mechanisms by which it may influence DNA repair processes. Chemists explore the stability and reactivity of Vitamin E nicotinate in various environments to improve its incorporation into nutritional supplements and fortified food products. Its interaction with other antioxidants is also a subject of research, as this has implications for the compound′s overall efficacy in different formulations. Furthermore, studies on Vitamin E nicotinate involve examining its role in lipid peroxidation and its potential to enhance the integrity of cell membranes.


vitamin e nicotinate (CAS 43119-47-7) References

  1. Determination of vitamin E acid succinate in biodegradable microspheres by reversed-phase high-performance liquid chromatography.  |  Martínez Sancho, C., et al. 2004. J Chromatogr Sci. 42: 43-8. PMID: 14965414
  2. Altered antioxidant status in peripheral skeletal muscle of patients with COPD.  |  Gosker, HR., et al. 2005. Respir Med. 99: 118-25. PMID: 15672860
  3. Highly selective trifluoromethylation of 1,3-disubstituted arenes through iridium-catalyzed arene borylation.  |  Liu, T., et al. 2012. Angew Chem Int Ed Engl. 51: 540-3. PMID: 22128037
  4. Metabolomics Studies to Assess Biological Functions of Vitamin E Nicotinate.  |  Marcocci, L. and Suzuki, YJ. 2019. Antioxidants (Basel). 8: PMID: 31083512
  5. Antioxidant Regulation of Cell Reprogramming.  |  Suzuki, YJ. and Shults, NV. 2019. Antioxidants (Basel). 8: PMID: 31434270
  6. Vitamin E and immune response. I. Enhancement of helper T cell activity by dietary supplementation of vitamin E in mice.  |  Tanaka, J., et al. 1979. Immunology. 38: 727-34. PMID: 316418
  7. Measurement of malonyldialdehyde production during sodium arachidonate-induced polymorphonuclear leukocyte aggregation.  |  Panus, PC., et al. 1985. J Pharmacol Methods. 13: 179-86. PMID: 3920449
  8. Effects of vitamin E on the aggregation and the lipid peroxidation of platelets exposed to hydrogen peroxide.  |  Higashi, O. and Kikuchi, Y. 1974. Tohoku J Exp Med. 112: 271-8. PMID: 4838067
  9. Effect of hyperthermia in combination with vitamin E and cyclic AMP on neuroblastoma cells in culture.  |  Rama, BN. and Prasad, KN. 1984. Life Sci. 34: 2089-97. PMID: 6328155
  10. A comparative study of the effect of vitamin E-nicotinate and the combination of vitamin E and nicotinic acid on the hydrogen peroxide-induced platelet aggregation.  |  Higashi, O. and Kikuchi, Y. 1977. Tohoku J Exp Med. 121: 81-4. PMID: 835140
  11. Vitamin E succinate inhibits proliferation and migration of retinal pigment epithelial cells in vitro: therapeutic implication for proliferative vitreoretinopathy.  |  Sakamoto, T., et al. 1996. Graefes Arch Clin Exp Ophthalmol. 234: 186-92. PMID: 8720718
  12. Copper Catalysis for Nicotinate Synthesis through β‐Alkenylation/Cyclization of Saturated Ketones with β‐Enamino Esters  |  Ling, F., Xiao, L., Fang, L., Lv, Y., & Zhong, W. 2018. Advanced Synthesis & Catalysis. 360(3): 444-448.
  13. Research progress in enzymatic synthesis of vitamin E ester derivatives  |  Zou, Z., Dai, L., Liu, D., & Du, W. 2021. Catalysts. 11(6): 739.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

vitamin e nicotinate, 100 mg

sc-280188
100 mg
$122.00