Icariin (CAS 489-32-7)
QUICK LINKS
Icariin is a naturally occurring compound classified as a flavonol glycoside, which is extensively studied in the field of botanical and natural products research. It is primarily found in the plant genus Epimedium. In research, Icariin is recognized for its role as a bioactive compound that can influence cellular pathways and gene expression. Studies involving Icariin focus on its effects on cell signaling mechanisms, particularly those related to the regulation of oxidative stress and the modulation of various enzymes and receptors. It is also of interest for its potential impact on bone metabolism and the maintenance of bone tissue in vitro. Researchers utilize Icariin to investigate its influence on the differentiation and proliferation of cells under controlled experimental conditions. The compound′s properties are central to advancing the understanding of the complex interactions between natural products and biological systems. Research on Icariin contributes to the broader field of phytochemistry and the exploration of plant-derived compounds for various applications.
Icariin (CAS 489-32-7) References
- The effect of icariin on bone metabolism and its potential clinical application. | Wang, Z., et al. 2018. Osteoporos Int. 29: 535-544. PMID: 29110063
- An outline for the pharmacological effect of icariin in the nervous system. | Jin, J., et al. 2019. Eur J Pharmacol. 842: 20-32. PMID: 30342950
- PI3K-AKT Signaling Activation and Icariin: The Potential Effects on the Perimenopausal Depression-Like Rat Model. | Cao, LH., et al. 2019. Molecules. 24: PMID: 31618892
- Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathways. | El-Shitany, NA. and Eid, BG. 2019. Biomed Pharmacother. 120: 109567. PMID: 31670031
- Pharmacological effects of icariin. | He, C., et al. 2020. Adv Pharmacol. 87: 179-203. PMID: 32089233
- Icariin and its metabolites regulate lipid metabolism: From effects to molecular mechanisms. | Wang, M., et al. 2020. Biomed Pharmacother. 131: 110675. PMID: 32861069
- Icariin-induced inhibition of SIRT6/NF-κB triggers redox mediated apoptosis and enhances anti-tumor immunity in triple-negative breast cancer. | Song, L., et al. 2020. Cancer Sci. 111: 4242-4256. PMID: 32926492
- Icariin alleviates osteoarthritis by regulating autophagy of chondrocytes by mediating PI3K/AKT/mTOR signaling. | Tang, Y., et al. 2021. Bioengineered. 12: 2984-2999. PMID: 34167449
- Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review. | Wang, S., et al. 2021. Drug Des Devel Ther. 15: 3619-3641. PMID: 34447243
- Icariin improves cutaneous wound healing in streptozotocin-induced diabetic rats. | Singh, WR., et al. 2022. J Tissue Viability. 31: 197-206. PMID: 34565677
- Research progress on icariin, a traditional Chinese medicine extract, in the treatment of asthma. | Yuan, JY., et al. 2022. Allergol Immunopathol (Madr). 50: 9-16. PMID: 34873891
- Icariin and its metabolites as potential protective phytochemicals against cardiovascular disease: From effects to molecular mechanisms. | Zeng, Y., et al. 2022. Biomed Pharmacother. 147: 112642. PMID: 35078094
- Impact of Icariin and its derivatives on inflammatory diseases and relevant signaling pathways. | Luo, Z., et al. 2022. Int Immunopharmacol. 108: 108861. PMID: 35597118
- Icariin: A Potential Neuroprotective Agent in Alzheimer's Disease and Parkinson's Disease. | Khezri, MR. and Ghasemnejad-Berenji, M. 2022. Neurochem Res. 47: 2954-2962. PMID: 35802286
- Bioavailability Improvement Strategies for Icariin and Its Derivates: A Review. | Szabó, R., et al. 2022. Int J Mol Sci. 23: PMID: 35886867
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Icariin, 1 g | sc-279198 | 1 g | $142.00 | |||
Icariin, 5 g | sc-279198A | 5 g | $413.00 | |||
Icariin, 10 g | sc-279198B | 10 g | $814.00 |