Date published: 2025-11-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

3,4-Dihydroxy-5-methoxy-benzoic acid (CAS 3934-84-7)

0.0(0)
Write a reviewAsk a question

Alternate Names:
5-Hydroxyvanillic acid; 3-O-Methylgallic acid
CAS Number:
3934-84-7
Purity:
≥97%
Molecular Weight:
184.15
Molecular Formula:
C8H8O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

3,4-Dihydroxy-5-methoxy-benzoic acid (DHMB) is a naturally occurring polyphenol compound found in various plant species, including in fruits and vegetables. It is an important intermediate in the biosynthesis of lignans, lignin, and other polyphenols. 3,4-Dihydroxy-5-methoxy-benzoic acid has been studied extensively for its potential anti-inflammatory, antioxidant, anti-cancer, and anti-diabetic activities. In addition, 3,4-Dihydroxy-5-methoxy-benzoic acid has been investigated for its ability to modulate enzyme activities, including those involved in the metabolism of carbohydrates and lipids.


3,4-Dihydroxy-5-methoxy-benzoic acid (CAS 3934-84-7) References

  1. Synthesis of 3-O-methylgallic acid a powerful antioxidant by electrochemical conversion of syringic acid.  |  Gargouri, OD., et al. 2013. Biochim Biophys Acta. 1830: 3643-9. PMID: 23434437
  2. Stability of anthocyanins- and anthocyanidins-enriched extracts, and formulations of fruit pulp of Eugenia jambolana ('jamun').  |  Sharma, RJ., et al. 2016. Food Chem. 190: 808-817. PMID: 26213042
  3. Flavanol plasma bioavailability is affected by metabolic syndrome in rats.  |  Margalef, M., et al. 2017. Food Chem. 231: 287-294. PMID: 28450008
  4. Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis.  |  Lee, S., et al. 2019. Sci Rep. 9: 8059. PMID: 31147608
  5. Kinetics and mechanism of syringic acid degradation initiated by hydroxyl radical and sulphate radical in the aqueous phase.  |  Tong, X., et al. 2020. Chemosphere. 256: 126997. PMID: 32473466
  6. In Vitro Gastrointestinal Digestion and Colonic Catabolism of Mango (Mangifera indica L.) Pulp Polyphenols.  |  Ordoñez-Díaz, JL., et al. 2020. Foods. 9: PMID: 33321767
  7. Intracellular pathways for lignin catabolism in white-rot fungi.  |  Del Cerro, C., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 33622792
  8. Effects of Wine and Its Microbial-Derived Metabolites on Intestinal Permeability Using Simulated Gastrointestinal Digestion/Colonic Fermentation and Caco-2 Intestinal Cell Models.  |  Zorraquín-Peña, I., et al. 2021. Microorganisms. 9: PMID: 34202738
  9. Systematically Exploring the Chemical Ingredients and Absorbed Constituents of Polygonum capitatum in Hyperuricemia Rat Plasma Using UHPLC-Q-Orbitrap HRMS.  |  Guan, H., et al. 2022. Molecules. 27: PMID: 35684459
  10. Characterization of two 1,2,4-trihydroxybenzene 1,2-dioxygenases from Phanerochaete chrysosporium.  |  Kato, H., et al. 2022. Appl Microbiol Biotechnol. 106: 4499-4509. PMID: 35687156
  11. Metabolomic Approach for Rapid Identification of Antioxidants in Clinacanthus nutans Leaves with Liver Protective Potential.  |  Ng, KS., et al. 2022. Molecules. 27: PMID: 35744776
  12. Comparative metabolomics analysis of pericarp from four varieties of Zanthoxylum bungeanum Maxim.  |  Cao, Y., et al. 2022. Bioengineered. 13: 14815-14826. PMID: 36274249
  13. Transcriptome and Metabolome Combined to Analyze Quinoa Grain Quality Differences of Different Colors Cultivars.  |  Liu, Y., et al. 2022. Int J Mol Sci. 23: PMID: 36361672
  14. Probiotic Yoghurt Enriched with Mango Peel Powder: Biotransformation of Phenolics and Modulation of Metabolomic Outputs after In Vitro Digestion and Colonic Fermentation.  |  Zahid, HF., et al. 2023. Int J Mol Sci. 24: PMID: 37239906
  15. Characterization and site-directed mutagenesis of aspen lignin-specific O-methyltransferase expressed in Escherichia coli.  |  Meng, H. and Campbell, WH. 1996. Arch Biochem Biophys. 330: 329-41. PMID: 8660663

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,4-Dihydroxy-5-methoxy-benzoic acid, 100 mg

sc-266894
100 mg
$53.00

3,4-Dihydroxy-5-methoxy-benzoic acid, 1 g

sc-266894A
1 g
$98.00

3,4-Dihydroxy-5-methoxy-benzoic acid, 5 g

sc-266894B
5 g
$347.00

3,4-Dihydroxy-5-methoxy-benzoic acid, 25 g

sc-266894C
25 g
$1469.00