Molecular structure of Vitexin, CAS Number: 3681-93-4
Vitexin (CAS 3681-93-4)
See product citations (4)
Alternate Names:
Apigenin 8-C-glucoside; 8-β-D-Glucopyranosyl-apigenin
Application:
Vitexin is an apigenin flavone glycoside
CAS Number:
3681-93-4
Purity:
≥97%
Molecular Weight:
432.38
Molecular Formula:
C21H20O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Vitexin is a naturally-occuring flavonoid and lignan compound that is identified in various plant sources. It is demonstrated to produce antioxidant effects in accord with other flavonoid compounds. Furthermore, it has anti-inflammatory, antidiabetic, anti-cancer, anti-microbial, anti-angiogenic, and anti-hypertensive activities. Vitexin exerts its effects by modulating a variety of cellular pathways, including the NF-κB pathway, the MAPK pathway, and the PI3K/Akt pathway. In addition, it has been found to inhibit the activity of a variety of enzymes, including cyclooxygenase-2, 5-lipoxygenase, and nitric oxide synthase.
Vitexin (CAS 3681-93-4) References
- The isolation and antioxidative effects of vitexin from Acer palmatum. | Kim, JH., et al. 2005. Arch Pharm Res. 28: 195-202. PMID: 15789751
- Photocontrol of Spirodela intermedia flavonoids. | McClure, JW. 1968. Plant Physiol. 43: 193-200. PMID: 16656751
- Preparative separation of vitexin and isovitexin from pigeonpea extracts with macroporous resins. | Fu, Y., et al. 2007. J Chromatogr A. 1139: 206-13. PMID: 17140590
- Vitexin, an HIF-1alpha inhibitor, has anti-metastatic potential in PC12 cells. | Choi, HJ., et al. 2006. Mol Cells. 22: 291-9. PMID: 17202857
- Neuroprotective effects of vitexin, a flavonoid, on pentylenetetrazole-induced seizure in rats. | Abbasi, E., et al. 2012. Chem Biol Drug Des. 80: 274-8. PMID: 22554436
- Apoptosis triggered by vitexin in U937 human leukemia cells via a mitochondrial signaling pathway. | Lee, CY., et al. 2012. Oncol Rep. 28: 1883-8. PMID: 22941432
- Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms. | Can, ÖD., et al. 2013. Eur J Pharmacol. 699: 250-7. PMID: 23099258
- Anti-nociceptive effect of vitexin mediated by the opioid system in mice. | Demir Özkay, U. and Can, OD. 2013. Pharmacol Biochem Behav. 109: 23-30. PMID: 23639588
- Vitexin inhibits inflammatory pain in mice by targeting TRPV1, oxidative stress, and cytokines. | Borghi, SM., et al. 2013. J Nat Prod. 76: 1141-9. PMID: 23742617
- Antinociceptive effects of vitexin in a mouse model of postoperative pain. | Zhu, Q., et al. 2016. Sci Rep. 6: 19266. PMID: 26763934
- Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. | Das, MC., et al. 2016. Sci Rep. 6: 23347. PMID: 27000525
- Absorption, metabolism, and bioactivity of vitexin: recent advances in understanding the efficacy of an important nutraceutical. | Peng, Y., et al. 2021. Crit Rev Food Sci Nutr. 61: 1049-1064. PMID: 32292045
- Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway. | Lee, JH., et al. 2020. Biochimie. 175: 58-68. PMID: 32445654
- Multitargeted Effects of Vitexin and Isovitexin on Diabetes Mellitus and Its Complications. | Abdulai, IL., et al. 2021. ScientificWorldJournal. 2021: 6641128. PMID: 33935599
- N-trimethyl chitosan coated targeting nanoparticles improve the oral bioavailability and antioxidant activity of vitexin. | Li, S., et al. 2022. Carbohydr Polym. 286: 119273. PMID: 35337500
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vitexin, 10 mg | sc-258332 | 10 mg | $72.00 | |||
Vitexin, 50 mg | sc-258332A | 50 mg | $175.00 | |||
Vitexin, 100 mg | sc-258332B | 100 mg | $302.00 | |||
Vitexin, 250 mg | sc-258332C | 250 mg | $496.00 |