Molecular structure of Trigonelline hydrochloride, CAS Number: 6138-41-6
Trigonelline hydrochloride (CAS 6138-41-6)
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Alternate Names:
1-Methylpyridinium-3-carboxylate hydrochloride; N-Methylnicotinic acid betaine hydrochloride
Application:
Trigonelline hydrochloride is an analytical standard for proteomics research
CAS Number:
6138-41-6
Molecular Weight:
173.60
Molecular Formula:
C7H7NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Trigonelline hydrochloride is a quaternary ammonium salt similar to niacin (vitamin B3) that is extensively studied in the fields of plant biology and food chemistry. Its presence in coffee and various plants makes it a compound of interest for investigating the impact of food processing on nutrient composition. In plant science, trigonelline hydrochloride is examined for its role as a growth hormone or germination enhancer, providing insights into plant development and metabolism. Its use in studies related to allelopathy, where it may influence the growth of surrounding plants, is also notable. Additionally, this compound is utilized in analytical chemistry as a reference standard for chromatographic analyses due to its well-defined properties and stability.
Trigonelline hydrochloride (CAS 6138-41-6) References
- Alkylpyridiniums. 1. Formation in model systems via thermal degradation of trigonelline. | Stadler, RH., et al. 2002. J Agric Food Chem. 50: 1192-9. PMID: 11853503
- Effects of coffee components on the response of GABA(A) receptors expressed in Xenopus oocytes. | Hossain, SJ., et al. 2003. J Agric Food Chem. 51: 7568-75. PMID: 14664509
- In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. | Daglia, M., et al. 2004. J Agric Food Chem. 52: 1700-4. PMID: 15030233
- Quantitative investigation of trigonelline, nicotinic acid, and nicotinamide in foods, urine, and plasma by means of LC-MS/MS and stable isotope dilution analysis. | Lang, R., et al. 2008. J Agric Food Chem. 56: 11114-21. PMID: 19007232
- Urinary N-methylpyridinium and trigonelline as candidate dietary biomarkers of coffee consumption. | Lang, R., et al. 2011. Mol Nutr Food Res. 55: 1613-23. PMID: 21618426
- Effect of coffee extracts on plasma fibrinolysis and platelet aggregation. | Naito, S., et al. 2011. Nihon Arukoru Yakubutsu Igakkai Zasshi. 46: 260-9. PMID: 21702337
- Comparative study of 2-hydroxy propyl beta cyclodextrin and calixarene as ionophores in potentiometric ion-selective electrodes for neostigmine bromide. | El-Kosasy, AM., et al. 2011. Talanta. 85: 913-8. PMID: 21726718
- Surface plasmon resonance based biosensors for exploring the influence of alkaloids on aggregation of amyloid-β peptide. | Kraziński, BE., et al. 2011. Sensors (Basel). 11: 4030-42. PMID: 22163834
- Experimental diabetes treated with trigonelline: effect on β cell and pancreatic oxidative parameters. | Zhou, J., et al. 2013. Fundam Clin Pharmacol. 27: 279-87. PMID: 22172053
- Preliminary studies on trigonelline as potential anti-Alzheimer disease agent: determination by hydrophilic interaction liquid chromatography and modeling of interactions with beta-amyloid. | Makowska, J., et al. 2014. J Chromatogr B Analyt Technol Biomed Life Sci. 968: 101-4. PMID: 24374010
- Analysis of coffee bean extracts by use of ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. | O'Driscoll, DJ. 2014. MethodsX. 1: 264-8. PMID: 27453823
- Trigonelline hydrochloride: A promising inhibitor for type I collagen fibrillation. | Rasheeda, K. and Fathima, NN. 2018. Colloids Surf B Biointerfaces. 170: 273-279. PMID: 29936380
- Coffee diterpenes kahweol acetate and cafestol synergistically inhibit the proliferation and migration of prostate cancer cells. | Iwamoto, H., et al. 2019. Prostate. 79: 468-479. PMID: 30569541
- Leishmania donovani Targets Host Transcription Factor NRF2 To Activate Antioxidant Enzyme HO-1 and Transcriptional Repressor ATF3 for Establishing Infection. | Saha, S., et al. 2021. Infect Immun. 89: e0076420. PMID: 33820818
- Inhibitory effect of chloroform extracts from Citrus aurantium L. var. amara Engl. on fat accumulation. | Li, XY., et al. 2021. Phytomedicine. 90: 153634. PMID: 34225246
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Trigonelline hydrochloride, 1 g | sc-258300 | 1 g | $52.00 | |||
Trigonelline hydrochloride, 5 g | sc-258300A | 5 g | $158.00 | |||
Trigonelline hydrochloride, 100 g | sc-258300B | 100 g | $2378.00 | |||
Trigonelline hydrochloride, 1 kg | sc-258300C | 1 kg | $20094.00 |