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S-tert-Butyl thioacetate (CAS 999-90-6)

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CAS Number:
999-90-6
Molecular Weight:
132.22
Molecular Formula:
C6H12OS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S-tert-Butyl thioacetate, a thioester compound, has found valuable applications in diverse scientific research endeavors. Its versatile nature enables its use in synthesizing bioactive compounds, creating innovative catalysts, and exploring enzyme-catalyzed reactions. Additionally, it plays a role in peptide and peptidomimetic synthesis, along with the generation of other small molecules. S-tert-Butyl thioacetate serves as a reliable reagent for the synthesis of heterocycles, including thiophenes, thiazoles, and thiolactones.


S-tert-Butyl thioacetate (CAS 999-90-6) References

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  3. Stereochemical Assignment of the Protein-Protein Interaction Inhibitor JBIR-22 by Total Synthesis.  |  Healy, AR., et al. 2015. Angew Chem Weinheim Bergstr Ger. 127: 4118-4122. PMID: 27087707
  4. Total Synthesis of the Broad-Spectrum Antibiotic Amycolamicin.  |  Meguro, Y., et al. 2022. J Am Chem Soc. 144: 5253-5257. PMID: 35297637
  5. Enantioselective Lewis Acid Catalyzed Michael Reactions of Alkylidene Malonates. Catalysis by C2-Symmetric Bis(oxazoline) Copper(II) Complexes in the Synthesis of Chiral, Differentiated Glutarate Esters  |  David A. Evans, Tomislav Rovis, Marisa C. Kozlowski, C. Wade Downey, and Jason S. Tedrow. 2000,. J. Am. Chem. Soc. 122, 38:, 9134–9142.
  6. Addition of ketene trimethylsilyl acetals to.alpha.,.beta.-unsaturated ketones: a new strategy for Michael addition of ester enolates  |  T. V. RajanBabu. 1984,. J. Org. Chem. 49, 12,: 2083–2089.
  7. Enolboration. 1. Dicyclohexylchloroborane/triethylamine as a convenient reagent for enolboration of ketones and other carbonyl derivatives  |  Herbert C. Brown, Raj K. Dhar, Kumaraperumal Ganesan, and Bakthan Singaram. 1992.: J. Org. Chem., 57, 2,: 499–504.
  8. Chiral synthesis via organoboranes. 33. The controlled reaction of B-alkyldiisopinocampheylboranes with aldehydes providing a convenient procedure for the enantiomeric enrichment of the boronic ester products through kinetic resolution  |  https://pubs.acs.org/doi/abs/10.1021/jo00028a021. 1992. J. Org. Chem., 57, 2:, 504–511.
  9. The S-Thioester Enolate/Imine Condensation: A Shortcut to β-Lactams  |   and Maurizio Benaglia, Mauro Cinquini, Franco Cozzi. February 2000. European Journal of Organic Chemistry. Volume2000, Issue4: Pages 563-572.
  10. Enantioselective Mannich-Type Reactions Using a Novel Chiral Zirconium Catalyst for the Synthesis of Optically Active β-Amino Acid Derivatives  |  Haruro Ishitani, Masaharu Ueno, and Shū Kobayashi. 2000,. J. Am. Chem. Soc. 122, 34,: 8180–8186.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S-tert-Butyl thioacetate, 1 g

sc-258095
1 g
$108.00